新穎非加壓式血壓量測技術研究

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姓名

林俊佑(Chun-yu Lin) 查詢紙本館藏

畢業系所

電機工程學系

論文名稱

新穎非加壓式血壓量測技術研究
(A Novel Cuffless Technique for Blood Pressure Measurement)

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摘要(中)

高血壓常上榜於國人每年十大死因，而其併發於腦中風、心肌梗塞、高血壓腎病變等心血管疾病。在國人社會壓力劇增的生活下，人人都是高危險群，這不單只是一個生理參數，更是人類需關切的議題。
本研究以量測心電訊號R波峰點和指尖的血量體積變化特徵點，求得脈搏傳遞時間(Pulse transit time, PTT)，再以胸骨上切跡與指尖距離除以傳遞時間，得出脈搏傳遞速度(Pulse wave velocity, PWV)，進而建立一套非侵入式、連續收縮壓(Systolic blood pressure, SBP)估測方法，研究方法以6位健康受測者(23.5±1.76歲)跑步運動誘發脈搏傳遞速度變化，並與市售血壓機(HEM-7320)所量測的收縮壓做線性迴歸分析，推得16位正常人(24.31±3.2歲)誤差4.29±5.26mmHg，與16位高血壓患者(60.93±12.06歲)誤差為39.88±23.62mmHg。
研究結果已能準確評估正常人血壓，誤差接近於市面電子血壓計可接受的範圍，而在高血壓患者血壓評估上，有明顯低估趨勢，可能與動脈阻塞程度有關。將來會致力於心血管疾病患者血壓評估，期待此方法能廣泛應用於不同族群的受測者。

摘要(英)

Hypertension was usually among the leading causes of death in Taiwan. Its complication combines with stroke, myocardial infarction, hypertension with hypertensive nephropathy, cardiovascular disease, etc. Everyone becomes High-risk groups. Blood pressure is not just a physiological parameters. It is an issue that we need to concern.
This study measures Electrocardiograph R wave and Photoplethysmogram characteristic points in fingertip to obtain pulse transit time. The distance between jugular notch and fingertip is divided by pulse transit time to obtain pulse wave velocity. In order to build a continuous noninvasively estimation systolic blood pressure method. Six subjects(23.5±1.76 age) go jogging to induce pulse wave velocity change and do linear regression on systolic blood pressure measured by HEM-7320.The error is 4.29±5.26mmHg. And sixteen hypertension patient (60.93±12.06 age)have the error 39.88±23.62mmHg.
Study results that we can exactly assess systolic blood pressure in normal subjects. The error range compared with electric sphygmomanometer can be accept. But we underestimate systolic blood pressure in hypertension subjects. It may be affected by arterial occlusion. In the future, we will focus on cardiovascular disease patient. And we expect this method can be applied in different groups.

關鍵字(中)

★ 收縮壓
★ 非侵入式

關鍵字(英)

論文目次

摘要 V
ABSTRACT VI
致謝 VII
圖目錄 X
表目錄 XII
第一章、緒論 1
1-1 前言 1
1-2 文獻回顧 2
1-2-1 侵入式 2
1-2-2 非侵入式 3
1-3 研究動機與目的 5
1-4 論文章節架構 5
第二章、生理簡介 6
2-1 血壓 6
2-2 光容積描記圖 7
2-3 心電圖 7
2-3-1 心電訊號原理 7
2-3-2 導程心電圖 9
第三章、實驗原理與設計 12
3-1 脈搏傳遞速度 12
3-2 系統架構 13
3-2-1 儀器介紹 14
3-3 正常受測者實驗 16
3-4 壢新醫院實驗 17
3-5 訊號處理 18
3-5-1 心電圖R波偵測 18
3-5-2 抓取光容積波形圖特徵點 19
3-6 收縮壓與脈搏傳遞速度關係 21
第四章、實驗結果 22
4-1 正常人運動實驗 22
4-2 正常人休息 24
4-3 壢新醫院正常人 25
4-4 壢新醫院高血壓 26
第五章、結果與未來展望 28
參考文獻 29
附錄一 31

參考文獻

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指導教授

李柏磊

審核日期

2015-8-24

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