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Chapter 1.
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46 Ultrafiltration.
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Chapter 2.
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2 Lee, T.; Kuo, C. S.; Chen, Y. H. Solubility, polymorphism, crystallinity, and crystal habit of acetaminophen and ibuprofen: By initial solvent screening. Pharm. Technol. 2006, 30(10), 72-92.
3 ICH guideline Q3C (R6) on impurities: guideline for residual solvents. European Medicines Agency, Science Medicines Health. (accessed August 9, 2019).
4 Sheldrick, G. M. SHELXL-2017, Program for Solution of Crystal Structures, University of Gottingen, Germany, 2017.
5 Sheldrick, G. M. Crystal structure refinement with SHELXL. Acta Crystallogr., Sect. C: Struct. Chem. 2015, 71, 3-8.
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7 United States Pharmacopeia and National Formulary (USP 35-NF 30). Tetracycline Hydrochloride. http://usp35.infostar.com.cn/uspnf/pub/data/v35300/usp35nf30s0_m81810.html#usp35nf30s0_m81810
Chapter 3.
1 Lee, T.; Kuo, C. S.; Chen, Y. H. Solubility, polymorphism, crystallinity, and crystal habit of acetaminophen and ibuprofen: By initial solvent screening. Pharm. Technol. 2006, 30(10), 72-92.
2 Benzyl alcohol.
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3 Dimethylformamide.
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5 ICH guideline Q3C (R6) on impurities: guideline for residual solvents. European Medicines Agency, Science Medicines Health. (accessed August 9, 2019)
6 National Center for Biotechnology Information. PubChem Database. Tetracycline hydrochloride.
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7 IR Spectroscopy Tutorial: Amines.
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8 IR Spectrum Table & Chart.
https://www.sigmaaldrich.com/technical-documents/articles/biology/ir-spectrum-table.html
9 Clegg, W.; Teat, S. J. Tetracycline Hydrochloride: A Synchrotron Microcrystal Study. Acta. Crystallogr. C. 2000, 11(11), 1343-1345.
10 United States Pharmacopeia and National Formulary (USP 35-NF 30). Tetracycline Hydrochloride. http://usp35.infostar.com.cn/uspnf/pub/data/v35300/usp35nf30s0_m81810.html#usp35nf30s0_m81810
11 Mullin, J. W. Crystallization, 4th ed.; Butterworth-Heinemann, 2001.
12 Genck, W. Make The Most of Antisolvent Crystallization. A number of factors can affect solids′ formation.
https://www.chemicalprocessing.com/articles/2010/210/ (accessed November 08, 2010).
13 Brubaker, J. How to Calculate HPLC Resolutions.
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14 Hair, M. L. Hydroxyl groups on silica surface. J Non Cryst Solids. 1975, 19, 299-309.
15 Reverchon, E.; Caputo, G.; Marco, I. D. Role of Phase Behavior and Atomization in the Supercritical Antisolvent Precipitation. Ind. Eng. Chem. Res. 2003, 42(25), 6406-6414.
Chapter 4.
1 Genck, W. Make The Most of Antisolvent Crystallization: A number of factors can affect solids′ formation.
https://www.chemicalprocessing.com/articles/2010/210/ (accessed November 08. 2010).
2 Robbe, C. L.; Jeb, S. T.; Donna, A. P.; Hullahalli, R. P.; Ajaz, S. H. Stability Profiles of Drug Products Extended beyond Labeled Expiration Dates. J Pharm Sci. 2006, 95(7), 1549-1560.
3 U.S. Food and Drug Administration. Don’t Be Tempted to Use Expired Medicines. https://www.fda.gov/drugs/special-features/dont-be-tempted-use-expired-medicines (accessed April 01, 2016)
4 Vapor-Liquid Equilibrium Calculator.
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6 Chen, Y.; Pan, Z.; Dong, Y. Measurements of Liquid−Liquid Equilibria for Quaternary Mixtures of Water, Methyltert-Butyl Ether, and Diisopropyl Ether with Methanol or Ethanol. Journal of Chemical & Engineering Data. 2005, 50(3), 1047-1051. |