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Chapter 1
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Chapter 2
1. Lin, P. Y.; Lee, H. L.; Chen, C. W.; Lee, T. Effects of baffle configuration and tank size on spherical agglomerates of dimethyl fumarate in a common stirred tank. Int. J. Pharm. 2015, 495(2), 886-894.
2. Zwietering, T. N. Suspending of solid particles in liquid by agitators. Chem. Eng. Sci. 1958, 8(3-4), 244-253.
3. Chen, C. W.; Lee, T. Round granules of dimethyl fumarate by three-in-one intensified process of reaction, crystallization, and spherical agglomeration in a common stirred tank. Org. Process Res. Dev. 2017, 21(9), 1326-1339.
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7. Lee, T.; Su, Y. C.; Hou, H. J.; Hsieh, H. Y. Spherical crystallization for lean solid-dose manufacturing (Part I). Pharm. Technol. 2010, 34(3), 72-75.
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Chapter 3
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6. Shanmugam, S. Granulation techniques and technologies: Recent progresses. BioImpacts 2015, 5(1), 55-63.
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15. Peña, R.; Nagy, Z. K. Process intensification through continuous spherical crystallization using a two-stage mixed suspension mixed product removal (MSMPR) system. Cryst. Growth Des. 2015, 15(9), 4225-4236
16. Tahara, K.; O’Mahony, M.; Myerson, A. S. Continuous spherical crystallization of albuterol sulfate with solvent recycle system. Cryst. Growth Des., 2015, 15(10), 5149-5156.
17. Lee, T.; Su, Y. C.; Hou, H. J.; Hsieh, H. Y. Spherical crystallization for lean solid-dose manufacturing (Part I). Pharm. Technol. 2010, March, 72-75.
18. Lin, P. Y.; Lee, H. L.; Chen, C. W.; Lee, T. Effects of baffle configuration and tank size on spherical agglomerates of dimethyl fumarate in a common stirred tank. Int. J. Pharm. 2015, 495(2), 886-894.
19. Li, J.-S.; Wu, S.-W.; Lu, K.-T. Study on preparation of intensive and spherical high bulk density nitroguanidine with controllable particle size. Propellants Explos. Pyrotech. 2016, 41(2), 312-320.
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21. Lee, T.; Chen, J. W.; Lee, H. L.; Lin, T. Y.; Tsai, Y. C.; Cheng, S.-L.; Lee, S.-W.; Hu, J.-C.; Chen, L.-T. Stabilization and spheroidization of ammonium nitrate: Co-crystallization with crown ethers and spherical crystallization by solvent screening. Chem. Eng. J. 2013, 225, 809-817.
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36. Thati, J.; Rasmuson, Å. C. On the mechanisms of formation of spherical agglomerates. Eur. J. Pharm. Sci. 2011, 42(4), 365-379.
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