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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/27786

    Title: Nonparametric identification of the minimum effective dose
    Authors: Chen,YI
    Contributors: 統計研究所
    Keywords: ONE-WAY LAYOUT
    Date: 1999
    Issue Date: 2010-06-29 19:33:35 (UTC+8)
    Publisher: 中央大學
    Abstract: We consider identifying the minimum effective dose (MED) in a dose-response study, where the MED is defined to be the lowest dose level producing an effect over that of the zero-dose control. Proposed herein is a nonparametric procedure based on the Mann-Whitney statistic incorporated with the step-down closed testing scheme. A numerical example demonstrates the feasibility of the proposed nonparametric procedure. Finally, the comparative results of a Monte Carlo level and power study for small sample sizes are presented and discussed.
    Relation: BIOMETRICS
    Appears in Collections:[統計研究所] 期刊論文

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