Solution structure of the ActD-5'-CCGTT(3)GTGG-3 ' complex: drug interaction with tandem G center dot T mismatches and hairpin loop backbone

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Title:	Solution structure of the ActD-5'-CCGTT(3)GTGG-3 ' complex: drug interaction with tandem G center dot T mismatches and hairpin loop backbone
Authors:	Chin,KH;Chen,FM;Chou,SH
Contributors:	生命科學研究所
Keywords:	SINGLE-STRANDED-DNA;ACTINOMYCIN-D-BINDING;CRYSTAL-STRUCTURE;GPC SITES;NMR;SEQUENCE;PAIRS;SPECTROSCOPY;REPEAT;DUPLEX
Date:	2003
Issue Date:	2010-07-07 11:40:11 (UTC+8)
Publisher:	中央大學
Abstract:	Binding of actinomycin D (ActD) to the seemingly single-stranded DNA (ssDNA) oligomer 5'-CCGTT(3) GTGG-3' has been studied in solution using high-resolution nuclear magnetic resonance (NMR) techniques. A strong binding constant (8 x 10(6) M-1) and high qu
Relation:	NUCLEIC ACIDS RESEARCH
Appears in Collections:	[Graduate Institute of Life Science] journal & Dissertation

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