Unique actinomycin D binding to self-complementary d(CXYGGCCY ' X ' G) sequences: duplex disruption and binding to a nominally base-paired hairpin

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Title:	Unique actinomycin D binding to self-complementary d(CXYGGCCY ' X ' G) sequences: duplex disruption and binding to a nominally base-paired hairpin
Authors:	Chen,FM;Sha,F;Chin,KH;Chou,SH
Contributors:	生命科學研究所
Keywords:	SINGLE-STRANDED-DNA;TETRANUCLEOTIDE SEQUENCES;GPC SITES;MODEL;DRUG;SPECIFICITIES;ASSOCIATION;COMPLEX;XGCY
Date:	2003
Issue Date:	2010-07-07 11:40:14 (UTC+8)
Publisher:	中央大學
Abstract:	Actinomycin D (ACTD) has been shown to bind weakly to the sequence -GGCC-, despite the presence of a GpC site. It was subsequently found, however, that d(CATGGCCATG) binds relatively well to ACTD but exhibits unusually slow association kinetics, contrary
Relation:	NUCLEIC ACIDS RESEARCH
Appears in Collections:	[Graduate Institute of Life Science] journal & Dissertation

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