Structural changes of lipid membrane induced by dehydration

Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/39199

Title:	Structural changes of lipid membrane induced by dehydration
Authors:	Chen,FY;Hung,WC
Contributors:	物理研究所
Keywords:	POLYMORPHISM;HYDRATION;LECITHIN;PHASES
Date:	1996
Issue Date:	2010-07-08 14:08:02 (UTC+8)
Publisher:	中央大學
Abstract:	The structural change of the lamellar lipid membrane dehydrated from the swelling L alpha-phase was studied by X-ray diffraction technique. The temperature and the water content of lipid membrane were controlled in a temperature-humidity chamber for Xray in-situ measurement. The result of the lamellar spacing revealed the existence of a first order phase transition induced by dehydration. Far from phase transition, X-ray diffraction patterns were analyzed, and the following changes in membrane structure caused by dehydration were observed: (1) water layers are thinning; (2) lipid bilayers expand in thickness; (3) lipid molecules in the monolayer of the single bilayer are packed more densely; (4) fluctuating tails of lipid hydrophobic chains shorten. More specifically, from its limiting thickness in full hydration, the lipid bilayer expands its thickness exponentially with water layer thinning in dehydration. A simple geometric model is proposed to explain such bilayer expansion induced by dehydration.
Relation:	CHINESE JOURNAL OF PHYSICS
Appears in Collections:	[Graduate Institute of Physics] journal & Dissertation

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