Improving polyp detection algorithms for CT colonography: Pareto front approach

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题名:	Improving polyp detection algorithms for CT colonography: Pareto front approach
作者:	Huang,A;Li,JA;Summers,RM;Petrick,N;Hara,AK
贡献者:	數據分析方法研究中心
关键词:	COMPUTER-AIDED DIAGNOSIS;TOMOGRAPHIC VIRTUAL COLONOSCOPY;SUPPORT VECTOR MACHINES;FINITE-SAMPLE SIZE;COLONIC POLYPS;COLORECTAL NEOPLASIA;FEATURE-SELECTION;NEURAL-NETWORKS;CLASSIFICATION;SEGMENTATION
日期:	2010
上传时间:	2012-03-27 17:50:13 (UTC+8)
出版者:	國立中央大學
摘要:	We investigated a Pareto front approach to improve polyp detection algorithms for CT colonography (CTC). A dataset of 56 CTC colon surfaces with 87 proven positive detections of 53 polyps sized 4-60 mm was used to evaluate the performance of a one-step and a two-step curvature-based region growing algorithm. The algorithmic performance was statistically evaluated and compared based on the Pareto optimal solutions from 20 experiments by evolutionary algorithms. The false positive rate was lower (p < 0.05) by the two-step algorithm than by the one-step for 63% of all possible operating points. While operating at a suitable sensitivity level such as 90.8% (79/87) or 88.5% (77/87), the false positive rate was reduced by 24.4% (95% confidence intervals 17.9-31.0%) or 45.8% (95% confidence intervals 40.1-51.0%), respectively. We demonstrated that, with a proper experimental design, the Pareto optimization process can effectively help in fine-tuning and redesigning polyp detection algorithms. (C) 2010 Elsevier B.V. All rights reserved.
關聯:	PATTERN RECOGNITION LETTERS
显示于类别:	[數據分析方法研究中心 ] 期刊論文

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