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| 題名: | Multiscale Entropy Analysis of Pulse Wave Velocity for Assessing Atherosclerosis in the Aged and Diabetic |
| 作者: | Wu,HT;Hsu,PC;Lin,CF;Wang,HJ;Sun,CK;Liu,AB;Lo,MT;Tang,CJ |
| 貢獻者: | 數據分析方法研究中心 |
| 關鍵詞: | ARTERIAL STIFFNESS;HEART-RATE;DYNAMICS;TIME;COMPLEXITY;RISK |
| 日期: | 2011 |
| 上傳時間: | 2012-03-27 17:50:40 (UTC+8) |
| 出版者: | 國立中央大學 |
| 摘要: | This study proposed a dynamic pulse wave velocity (PWV)-based biomedical parameter in assessing the degree of atherosclerosis for the aged and diabetic populations. Totally, 91 subjects were recruited from a single medical institution between July 2009 and October 2010. The subjects were divided into four groups: young healthy adults (Group 1, n = 22), healthy upper middle-aged adults (Group 2, n = 28), type 2 diabetics with satisfactory blood sugar control (Group 3, n = 21), and unsatisfactory blood sugar control (Group 4, n = 20). A self-developed six-channel electrocardiography (ECG)-PWV-based equipment was used to acquire 1000 successive recordings of PWV(foot) values within 30 min. The data, thus, obtained were analyzed with multiscale entropy (MSE). Large-scale MSE index (MEI(LS)) was chosen as the assessment parameter. Not only did MEI(LS) successfully differentiate between subjects in Groups 1 and 2, but it also showed a significant difference between Groups 3 and 4. Compared with the conventional parameter of PWV(foot) and MEI on R-R interval [i.e., MEI (RRI)] in evaluating the degree of atherosclerotic change, the dynamic parameter, MEI(LS) (PWV), could better reflect the impact of age and blood sugar control on the progression of atherosclerosis. |
| 關聯: | IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING |
| 顯示於類別: | [數據分析方法研究中心 ] 期刊論文
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