English  |  正體中文  |  简体中文  |  Items with full text/Total items : 67621/67621 (100%)
Visitors : 23089754      Online Users : 277
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/50773


    Title: A cohort study to evaluate the effectiveness of laparoscopic-guided local injection of etoposide in the management of women with unruptured tubal pregnancy
    Authors: Chen,CH;Lee,WL;Chiu,LH;Sun,HD;Liu,WM;Wang,PH
    Contributors: 生命科學系
    Keywords: ECTOPIC PREGNANCY;INTERSTITIAL PREGNANCY;METHOTREXATE TREATMENT;DOSE METHOTREXATE
    Date: 2011
    Issue Date: 2012-03-27 18:09:53 (UTC+8)
    Publisher: 國立中央大學
    Abstract: Objective: To assess the feasibility of laparoscopic-guided local injection of etoposide or methotrexate (MTX) in the management of unruptured tubal pregnancy and compare the effectiveness of the two regimens. Design: Retrospective cohort study. Setting: Medical center. Patient(s): Thirty-one women with laparoscopically diagnosed unruptured tubal pregnancy. Intervention(s): A regimen of etoposide 50 mg via laparoscopic-guided local injection (n = 17) compared with a conventional MTX 50 mg regimen (n = 11), after 3 patients were excluded (2 refusals and 1 with salpingostomy). Main Outcome Measure(s): Serial serum beta-hCG levels and the success rate in both groups. Result(s): General characteristics of the patients were similar in both groups. The overall success rate was 96.4% (27 of 28). The duration between treatment and nadir of serum beta-hCG level (<5 mIU/mL) was significantly shorter in the etoposide group than in the MTX group (19.7 +/- 13.0 days vs. 33.4 +/- 8.1 days). No patient in the etoposide group and only 1 in the MTX group needed reintervention, which led to 100% and 91% success rates for the etoposide and MTX groups, respectively. Three women in the etoposide group had subsequently successful term deliveries. Conclusion(s): Both regimens-etoposide 50 mg and MTX 50 mg via laparoscopic-guided local injection-were acceptable in the management of women with unruptured tubal pregnancy because of their similar and high success rates. More studies are needed to confirm this observation. (Fertil Steril (R) 2011;96:654-8. (C)2011 by American Society for Reproductive Medicine.)
    Relation: FERTILITY AND STERILITY
    Appears in Collections:[生命科學系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML644View/Open


    All items in NCUIR are protected by copyright, with all rights reserved.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback  - 隱私權政策聲明