English  |  正體中文  |  简体中文  |  Items with full text/Total items : 70548/70548 (100%)
Visitors : 23160782      Online Users : 222
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/51071


    Title: From laws of inference to protein folding dynamics
    Authors: Tseng,CY;Yu,CP;Lee,HC
    Contributors: 系統生物與生物資訊研究所
    Keywords: TRP-CAGE;INFORMATION GEOMETRY;MOLECULAR-DYNAMICS;MINIPROTEIN;SIMULATION;MODEL;TIME
    Date: 2010
    Issue Date: 2012-03-27 18:20:31 (UTC+8)
    Publisher: 國立中央大學
    Abstract: Protein folding dynamics is one of major issues constantly investigated in the study of protein functions. The molecular dynamic (MD) simulation with the replica exchange method (REM) is a common theoretical approach considered. Yet a trade-off in applying the REM is that the dynamics toward the native configuration in the simulations seems lost. In this work, we show that given REM-MD simulation results, protein folding dynamics can be directly derived from laws of inference. The applicability of the resulting approach, the entropic folding dynamics, is illustrated by investigating a well-studied Trp-cage peptide. Our results are qualitatively comparable with those from other studies. The current studies suggest that the incorporation of laws of inference and physics brings in a comprehensive perspective on exploring the protein folding dynamics.
    Relation: PHYSICAL REVIEW E
    Appears in Collections:[系統生物與生物資訊研究所] 期刊論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML511View/Open


    All items in NCUIR are protected by copyright, with all rights reserved.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback  - 隱私權政策聲明