中大機構典藏-NCU Institutional Repository-提供博碩士論文、考古題、期刊論文、研究計畫等下載:Item 987654321/62683
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 69561/69561 (100%)
造訪人次 : 23085216      線上人數 : 831
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋


    請使用永久網址來引用或連結此文件: http://ir.lib.ncu.edu.tw/handle/987654321/62683


    題名: 計算系統生物學方法來模擬急性與慢性發炎;Computational systems biology to model acute and chronic inflammation
    作者: 王孫崇
    貢獻者: 國立中央大學系統生物與生物資訊研究所
    關鍵詞: 物理;資訊科學;軟體;生物技術(醫)
    日期: 2013-12-01
    上傳時間: 2014-03-17 11:58:21 (UTC+8)
    出版者: 行政院國家科學委員會
    摘要: 研究期間:10208~10307;Interactions among biomolecules such as genes, proteins and metabolites form a complex network consisting of nested feedback and feedforward loops. Comprehension of the behavior of a whole biological system through dynamics of the interacting parts in isolation has been regarded as less successful. Approaches of systems biology aim to address the complexity issue by integrating functional knowledge from genome-scale experimental data and mathematic models with mutl-level dynamic equations. Inflammation is an evolutionarily conserved innate immune response of higher organisms to microbes or injuries. Acute inflammation resolves inflection and promotes wound healing. Unresolved inflammation due to persistent infection or dysfunctional immunity undermines healing, leading to chronic inflammation. Inflammatory response exhibits circadian rhythms in clinical observations. Stress, psychological or physiological, suppresses immunity. We propose to study effects of temporal stress profiles on inflammatory response through computational systems biology approaches.
    關聯: 財團法人國家實驗研究院科技政策研究與資訊中心
    顯示於類別:[系統生物與生物資訊研究所] 研究計畫

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    index.html0KbHTML318檢視/開啟


    在NCUIR中所有的資料項目都受到原著作權保護.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋  - 隱私權政策聲明