銅(I)催化碳-氮偶合反應之研究

Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/69251

Title:	銅(I)催化碳-氮偶合反應之研究
Authors:	李昕鴻;Li,Hsin-hung
Contributors:	化學學系
Keywords:	碳-氮偶合反應;銅一價催化;1,10-二氮雜菲
Date:	2015-11-30
Issue Date:	2016-01-05 17:31:22 (UTC+8)
Publisher:	國立中央大學
Abstract:	以二苯胺類/鹵化苯/碘化銅/1,10-二氮雜菲/叔丁醇鹼進行一價銅碳-氮偶合反應已被研究多年,但對於某些特定地方還是有所不足。而本篇論文以此系統為研究基礎就反應溶劑極性的使用、反應選擇性上的差異著手,進而發現使用極性反應溶劑在此系統上是極為糟糕的, 不只產率低,甚至還產生碳-碳偶合之自由基產物,導致反應結果紊亂。而在反應選擇性上發現自由基路徑的產生左右著不同相位產物的產生。而後於二苯胺鹽/鹵化苯/碘化銅系統上發現加入 1,10-二氮雜菲對反應是有所抑制的,而此一結果與二苯胺類/鹵化苯/碘化銅/叔丁醇鹼系統相反。之後以反應動力學串聯兩個系統,以巨觀的方式直接瞭解兩系統之全貌。;The Copper(I) C-N cross coupling catalyzed by NPh2H/ArI/CuI/1,10- Phenanthroline(Phen)/MOtBu system has been studied for many years, but for some specific places or inadequate. This thesis focus on the studies of polar solvent effect and reaction selectivity. Using polar solvent causes low yield and C-C coupling products, which are generated by free radical path. The reaction selectivity experiments indicate free radical path control specific product. After the reaction kinetics of the two systems, with direct knowledge of the macroscopic picture of the way the two systems.
Appears in Collections:	[Graduate Institute of Chemistry] Electronic Thesis & Dissertation

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