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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/69482

    Title: 患有慢性阻塞肺病會增加得到敗血症的風險: 以台灣全人口基礎的前瞻式世代研究;Increased risk of sepsis among patients with chronic obstructive pulmonary disease patients: A population-based prospective cohort study in Taiwan
    Authors: 邱鼎文;Chiu,Ding-Wen
    Contributors: 資訊工程學系在職專班
    Keywords: 敗血症;慢性阻塞肺病;sepsis;chronic obstructive pulmonary disease
    Date: 2016-01-29
    Issue Date: 2016-03-17 20:44:58 (UTC+8)
    Publisher: 國立中央大學
    Abstract: 慢性阻塞性肺疾病(COPD)是一種常見的健康問題,有很高的發病率及死亡率,其特
    料庫抓取100 歲以下的新發慢性阻塞性肺疾病病患,再來排除一些會影響我們研究的病患,
    的患者得到敗血症的風險是比較高的(HR=1.50,95% CI=1.42-1.59),而在我們控制了肺
    炎之後,得到敗血症的風險會降低(HR=1.21,95% CI =1.15-1.28),所以肺炎是導致敗血
    更高的風險得到敗血症,尤其是年齡在60 歲以上的患者。;Chronic obstructive pulmonary disease (COPD) is a major health problem and a leading
    cause of morbidity and mortality, which is characterized by airflow limitation that is progressive
    and not fully reversible. Sepsis is a systemic inflammatory response to infection. The fatality rate
    of patients with sepsis has continues as high as 30%-60% worldwide. In a recent study, COPD
    are at increased risk of contracting pneumonia, pneumonia and sepsis are interrelated because
    severe cases of pneumonia can eventually lead to sepsis. Thus pneumonia is acts as an
    intermediary between COPD and the sepsis, it is an important key factor. Thus, we select ≦100
    years newly COPD patients from National Health Insurance Research Database (NHIRD),
    exclude some patients who affect our study and evaluate the effects of comorbidities or
    pneumonia with COPD on the sepsis risk. Finally, we analyzed the patients with COPD had an
    increased risk for sepsis in this cohort (HR=1.50, 95% CI=1.42-1.59), after controlling for
    pneumonia, the risk was attenuated (HR=1.21, 95% CI =1.15-1.28). Pneumonia was a very
    strong factor of sepsis. However, the elderly COPD patients were at a higher hazard for sepsis
    than the younger, especially in the group aged >60 years.
    Appears in Collections:[資訊工程學系碩士在職專班 ] 博碩士論文

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