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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/70046


    Title: 組織發炎與腎臟癌發生機制研究;Study of Tissue Inflammation and the Initiation of Renal Cell Carcinoma
    Authors: 徐沺
    Contributors: 系統生物與生物資訊研究所
    Keywords: VHL;腎臟病;發炎與癌症;VHL;kidney disease;inflammation and cancer;基礎醫學
    Date: 2016-03-29
    Issue Date: 2016-03-30 11:12:42 (UTC+8)
    Publisher: 科技部
    Abstract: 腎臟病與腎臟癌是台灣一個嚴重的健康問體。台灣是末期腎臟病比例世界最高國家。 腎臟病也是腎臟癌的已知致病因素(risk factor) 。腎臟病只能控制惡化,不能治癒。 傳統化療與放射線療對腎臟癌也無效。因為症狀少,早期診斷也很困難。40-50% 的腎 臟腫瘤會轉成惡化, 惡性腎臟癌病人的5 年生存率只有10%。這麽令人悲觀的數據也 指出對於腎臟病生物學了解的迫切須要。腎臟疾病的一個重要特性是它與一個抑癌基 因, 希佩爾-林道基因 (VHL),有很密切的關係。VHL 基因突變會導致囊腫性腎臟 病,也是腎臟透;Kidney disease and cancer constitute a serious health problem in Taiwan. Taiwan has the world's highest rate of end-stage renal disease, which in turn is the known risk factor for kidney cancer. Kidney disease has no cure. Traditional radiation and chemo-;研究期間:10408~10507
    Relation: 財團法人國家實驗研究院科技政策研究與資訊中心
    Appears in Collections:[Institute of Systems Biology and Bioinformatics] Research Project

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