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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/7077


    Title: 實驗室晶片整合之設計與製作
    Authors: 鄭世偉;Shi-Wei Zheng
    Contributors: 光電科學研究所
    Keywords: 介電質電濕式驅動;導模共振式光學感測;GMR;EWOD
    Date: 2009-07-08
    Issue Date: 2009-09-22 10:36:44 (UTC+8)
    Publisher: 國立中央大學圖書館
    Abstract: 在生命科學與醫學研究中,樣品的分析通常包括三個典型步驟,即:樣品分離處理、生物化學反應、結果檢測和分析。現今的實驗室晶片通常只具有執行單一步驟的能力,因此在進行樣品的分析的實驗時,常常需要將專門的樣品晶片、反應晶片、檢測晶片以及微泵和微閥門等元件結合,這不僅耗時、耗費成本而且也可能對實驗造成影響。   因此,本研究提出將驅動器與感測器結合的概念,將介電質電濕式(electrowetting on dielectric, EWOD)微流體系統與導模共振(guided-mode resonance)感測整合至微小晶片上,並且利用整合後的晶片來進行不同濃度的蔗糖液滴訊號量測實驗。由實驗結果得知,本研究製作的晶片不僅成功的將驅動器與感測器結合,而且還能做到動態與即時的量測效果。In life science and medicine research, the assay of the testing samples includes three steps : sample preparation、biochemistry reaction、examination and analysis. Currently, the biochips working with single function require other device such as sample chips、reaction chips、assay chips、micro pump、micro-valve and so on, to perform experiments on assay of the testing sample that are time-consuming and money-wasting. In this work, we propose the concept about integration of actuator and sensor, so the electro-wetting on dielectric (EWOD) micro-fluidic system is integrated with guide-mode resonance (GMR) sensors for the assay of sucrose aqueous solution. The optical spectrum analyzer (OSA) data reveals that the integrated chip works normally, also can achieve in-situ detection.
    Appears in Collections:[光電科學研究所] 博碩士論文

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