目前臨床上對於不同斷裂部位的骨折，發展出對應的樣式骨板與骨釘系統作為固定治療方式，為了解骨板於使用上的力學行為，並且給予骨科醫師作為選擇植入物之依據，因此本研究包含植體之骨板與骨釘於骨組織中的解析解推導，考慮植體於骨骼系統內的簡化模型承受簡單外力形式；使用COMSOL Multiphysics軟體分析含植體之骨組織有限元素模擬技術建立與驗證，探討植體及骨頭中的應力值與應變值。另外，也針對實驗樣品建立有限元素模型，計算植體結構強度，探討骨骼、骨板與骨釘的變形、應力與應變，此結果將作為植體選擇與鎖固分析的依據。本研究藉由COMSOL App建立器(Application Builder)分析不同骨板與骨釘的參數設定所呈現的應力及應變，可作為植體的材料選擇、螺釘數量的選擇及接觸式或非接觸式骨板的選擇；而從實際Sawbones模型得知螺釘的數目與位置，會影響骨板的應力分佈，可提供醫師手術前規劃的初步參考資訊。;At present, several types of implant (plate and screws) have been developed for the corresponding bone fractures at different sites. In order to understand the mechanical behavior of bone plate and to give surgeons some suggestions of selecting implants, this study includes the following aspects. The simplified model of bone-implant system subjected to an eccentric axial compression was derived in analytical form. In addition, the stress and strain in bone and implant were investigated using COMSOL Multiphysics software. Furthermore, the computed tomography (CT)-based finite element model was established to calculate the strength of the implant as well as the deformation, stress and strain of the bone, plate and screws. These results can serve as guidance for the selecting implant. This study also uses COMSOL Application Builder to analyze the stress and strain of a screw-plate fixation for different parameters such as the material of the implant, the number of screws and contact or non-contact plate. The CT-based model reveals the number and location of screws affected the stress distribution of the bone plate. It can provide preliminary reference information for clinicians before surgery.
