天然物合成與氮環丙烷相關合成方法之發展(1/2);Synthesis of Natural Products and Development of Aziridine-Related Methodology(I)

Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/78181

Title:	天然物合成與氮環丙烷相關合成方法之發展(1/2);Synthesis of Natural Products and Development of Aziridine-Related Methodology(I)
Authors:	侯敦仁
Contributors:	國立中央大學化學系
Keywords:	天然物合成二氫呋喃置換反應肌醇環丙烷;Natural product synthesis;dihydrofuran;metathesis;inositol;aziridine
Date:	2018-12-19
Issue Date:	2018-12-20 11:09:48 (UTC+8)
Publisher:	科技部
Abstract:	我們計劃合成幾種天然物，並發展利用氮丙烷開環反應的合成方法。目標分子為最近發現的幾種具有生物活性(抗生素和抗癌活性)的天然物，其合成也尚未被報導。其他合成標的物有 α-Galcer 類似物，為有希望的免疫系統調節劑與抗生素的類糖部分。 ;We plan to synthesize several natural products and develop several synthetic methods utilizing the ring-opening of aziridine in this proposal. Several of the target molecules (natural products) with biological activities, including antibiotic and anti-cancer, are recently discovered and their syntheses have not been reported yet. Other target molecules are alpha-Galcer analogues, promising immune system modulators and unusal sugars, parts of antibiotics.
Relation:	財團法人國家實驗研究院科技政策研究與資訊中心
Appears in Collections:	[Department of Chemistry] Research Project

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