關鍵詞：痤瘡丙酸桿菌，表皮葡萄球菌，鼠李糖乳桿菌，大腸桿菌，肺炎克雷伯菌，金黃色葡萄球菌，椰油酸甘油酯，一水合乳糖乳糖，直鏈澱粉 ;3 Abstract The overgrowth of Cutibacterium acnes (C. acnes), a commensal skin bacterium, has been associated with the progression of acne vulgaris. Human skin and gut bacteria can produce electricity by fermentation. Based on this electricity producing ability of bacteria we have tested to check whether Staphylococcus epidermidis (S. epi) fermentation with Amylose can inhibit the growth of C. acnes by producing electricity. We found that human gut and skin bacteria can produce significantly higher electricity when the fermentation mediated by various prebiotics. We have selected glucose and glycerol which are most common prebiotics for measuring the production of electricity of bacteria from gut Lactobacillus rhamnosus (L. rhamnosus), Escherica coli (E. coli), Klebseilla pneumoniae (K. pneumoniae) and bacteria from skin C. acnes, S. epi, Staphylococcus aureus (S. aureus). We have tested 3 different prebiotics Glyceryl cocoate (PEG- 7), Alpha lactose monohydrate (ALM), Amylose (Amy) for measuring prebiotic mediated production of electricity from S. epi. The Amylose mediated fermentation of S. epi has shown the highest production of electricity. Our results demonstrated that S. epi can mediate fermentation of Amylose to enhance its inhibitory effects on C. acnes growth by producing electicity in vivo and in vitro. Keywords: C. acnes, S. epi, L. rhamnosus, E. coli, K. pneumoniae, S. aureus, PEG-7, ALM, Amy
