近年來土壤與地下水遭到有害化學物質污染事件層出不窮,對環境與人體健康安全造成威脅,因此對於建立一套有害化學物質污染導致人體健康風險的評估操作軟體是非常重要的。在執行健康風險評估過程中需進行暴露評估,宿命傳輸模式常用來進行關切污染物於環境介質的傳輸,以預測計算暴露劑量。本研究所採用的宿命傳輸模式之特點為可考量不同類型的污染源函數與各個污染物的遲滯因子,更適用於真實環境條件下的污染傳輸情境,減少因過於簡化的條件造成暴露濃度預測上的誤差。傳輸模式與健康風險評估模式多因計算量龐大而使用Fortran程式語言,然而許多使用人員並不熟悉此語言的操作方法,造成評估人體健康風險的使用門檻較高,為了使傳輸模式與健康風險評估模式更容易被使用,本研究透過C Sharp (C#)程式語言建構圖形使用者介面,並結合地下水污染傳輸與健康風險評估模組,可讓使用者更易操作與分析模擬結果。本研究的目的為開發一個地下水污染場址健康風險評估軟體,結合最先進的多物種遷移分析模型與健康風險評估計算模組,可適用關切污染物與其序列降解生成產物的污染場址,且可根據場址污染源的特性採用不同的污染濃度的函數,並成功結合了圖形使用者介面、最新的數學模式與健康風險評估模組以進行場址之風險評估。此軟體降低了過去模式的使用門檻,可提供給國內、外相關領域學者、研究人員、工程師與政府人員更友善的使用環境,以提昇台灣地下水污染整治模式的競爭力。;In recent years, soil and groundwater have been polluted by toxic chemicals, posing threats to the environment and life safety. Therefore, software for health risk assessment is proposed and developed. In exposure assessment of health risk assessment, the fate and transport model is often used to predict the constituents of concern in the environmental medium to calculate the exposure dose. This study applies the analytical models to simulate the multispecies transport behaviors. Different retardation factors for individual species and different types of source functions are considered in this model, which is more suitable for the real situation. The transport model and health risk assessment in previous research mostly uses the Fortran programming language due to a large number of calculations. Most users are not familiar with the operation method of this language, resulting in a higher threshold for the use of health risk assessment. This study develops the graphical user interface with C Sharp (C#), combines the transport and health risk assessment, can make it easier for users to operate and analyze the simulation results. The developed software can be applied to contaminated sites and can use different source histories according to the situation of the contaminated sites, and successfully combines the graphical user interface, the latest mathematical modules and health risk assessment modules for human health risk assessment. This software can be provided to scholars, researchers, engineers and government in related fields to enhance the competitiveness of groundwater pollution remediation model.