許多生物系統由嵌入被動流體中的活性纖維狀顆粒組成。例如，游 動的桿狀細菌和細胞皮質。這些系統的長期動力學在本研究中被建 模為活性滲透極性凝膠。該模型中的流體力學變量包括活性成分的 密度、動量密度以及指示纖維局部方向的導向場。在本論文的第一 部分中，使用廣義流體動力學理論推導出該系統的運動方程。在第 二部分中，我們將模型應用於一個具有橫向約束的準二維系統。類 似的單一組分活性凝膠模型已被用於解釋在匯合細胞單層中觀察到 的自發流動。我們的模型預測，當活性纖維的密度允許變化時，系 統中也會發生自發的振盪流動。;Many biological systems are composed of active filamentous particles embedded in a pas- sive fluid. Examples include swimming rod-shaped bacteria and cell cortex. The long-time dynamics of such systems are modeled in this work as active permeating polar gels. The density of active components, the momentum density, and the director field which indicates the local direction of the filaments are the hydrodynamic variables in this model. In the first part of this thesis, the equations of motion for this system using generalized hydrodynamic theory. In the second part of this thesis, we apply our model in a quasi two-dimension system with lateral confinement. Similar model for a one-component active gel has been applied to explain the observed spontaneous flow in confluent cell monolayers. Our model predicts that when the density of active filaments is allowed to vary, spontaneous oscillatory flow in the system can also happen.
