博碩士論文 110521089 詳細資訊




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姓名 張博翔(Po-Hsiang Chang)  查詢紙本館藏   畢業系所 電機工程學系
論文名稱 穿戴式低能量脈衝電磁場設備開發及其應用
(Development and application of a wearable low-energy pulsed electromagnetic field device)
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摘要(中) 自主神經系統在人體健康中扮演著重要的調節作用。自主神經系統(Autonomic nervous system,ANS)失調可能導致許多疾病。近年來,運用脈衝電磁場(Pulsed electro magnetic fields,PEMF)調節自主神經系統的平衡引起了極大的關注。PEMF治療不需要直接接觸用戶的身體,是一種非侵入性、非接觸和非熱療法,在長時間使用下不會對皮膚造成損傷。然而,目前的PEMF設備由於需要大尺寸的磁場線圈來產生足夠的磁場強度,因此設備體積較為龐大。本研究提出了一種使用軟性印刷電路板(Flexible printed circuit board,FPCB)製造的多層PEMF裝置。所提出系統的刺激線圈具有可彎曲、薄、輕、磁場強度高的優點。PEMF系統已應用於通過姿勢誘導的交感/副交感變化調節ANS平衡的傾斜桌測試中。PEMF刺激顯示在調節ANS平衡方面具有顯著的改善作用。與非PEMF條件相比,頻譜心率變異指標LF、HF和LF / HF比值分別為62.02 ± 19.35 vs. 71.17 ± 14.34、37.98 ± 19.35 vs. 28.83 ± 14.34和2.62 ±2.41 vs. 4.03 ± 3.96,表明PEMF刺激對ANS調節具有效果。所提出的可穿戴式PEMF設備具有良好的穿戴性,並可以與衣服結合使用,這種技術能夠在未來的人體研究中實現長期刺激。
摘要(英) The autonomic nervous system (ANS) plays a crucial role in maintaining human health, and dysautonomia can lead to various diseases. Pulsed electromagnetic field (PEMF) therapy has emerged as a promising approach for regulating ANS balance. However, existing PEMF devices are typically bulky due to the large size of the magnetic coil required to generate sufficient magnetic strength for stimulation. In this study, we propose a multi-layer PEMF device fabricated using flexible printed circuit board (FPCB) technology. The stimulation coil of our device offers advantages such as flexibility, thinness, lightweight, and high magnetic field intensity.
This study applied our PEMF system to regulate ANS balance by conducting tilt-table tests to induce posture-induced sympathetic/parasympathetic changes. The results demonstrated a significant improvement in ANS balance with PEMF stimulation. When comparing the PEMF and non-PEMF conditions, the spectral heart rate variability (HRV) indices, including LF (low frequency), HF (high frequency), and LF/HF ratio, showed significant changes. Specifically, LF values were 62.02 ± 19.35 vs. 71.17 ± 14.34, HF values were 37.98 ± 19.35 vs. 28.83 ± 14.34, and LF/HF ratio values were 2.62 ± 2.41 vs. 4.03 ± 3.96, respectively. These results highlight the effectiveness of PEMF stimulation in regulating ANS activity.
The proposed wearable PEMF device offers excellent wearability and can be seamlessly integrated with clothing, which enables the long-term stimulation in future human studies.
關鍵字(中) ★ 脈衝電磁場
★ 自主神經系統
★ 心率變異度
★ 可穿戴式裝置
關鍵字(英) ★ Pulsed electromagnetic field
★ Autonomic nervous system
★ Heart rate variability
★ Wearable device
論文目次 中文摘要 i
Abstract ii
目錄 iii
圖目錄 v
表目錄 vii
第一章 緒論 1
1-1 研究動機與目的 1
1-2 文獻探討 3
1-3 論文章節架構 5
第二章 原理介紹 6
2-1 心電圖原理 6
2-2 自主神經系統 7
2-3 心率變異度指標 8
2-3-1 時域分析(Time domain analysis) 8
2-3-2 頻域分析(Frequency domain analysis) 9
2-4 脈衝電磁場刺激 11
2-5 傾斜桌試驗 13
第三章 研究設計與方法 14
3-1 系統架構 14
3-1-1 脈衝電磁場刺激系統 15
3-1-2 刺激波型序列設計 16
3-1-3 多層刺激線圈設計 19
3-2 生理訊號紀錄器硬體架構 26
3-3 實驗設計和受試者 27
3-4 心電訊號分析 28
第四章 結果與討論 32
4-1 實驗結果 32
4-2 實驗討論 36
第五章 結論與未來展望 39
參考文獻 40
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指導教授 李柏磊(Po-Lei Lee) 審核日期 2023-11-1
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