Assessment of the pericardia of four mammalian species fixed with an epoxy compound as pericardial heterografts

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Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/26538

Title:	Assessment of the pericardia of four mammalian species fixed with an epoxy compound as pericardial heterografts
Authors:	Chen,CN;Wu,CC;Tsai,CC;Sung,HW;Chang,Y
Contributors:	化學工程與材料工程學系
Keywords:	BIOLOGICAL VALVED CONDUIT;BOVINE PERICARDIUM;TEMPERATURE
Date:	1997
Issue Date:	2010-06-29 17:30:25 (UTC+8)
Publisher:	中央大學
Abstract:	Pericardia from varying mammalian species, chemically modified with a crosslinking reagent, have been used in the cardiovascular surgery as a biological patch or in the construction of heart valve prosthesis, The study was to compare the thermal stability, mechanical strength, wettability, surface tension, and resistance against collagenase degradation of the pericardia from calves, sheep, pigs, and dogs fixed with an epoxy compound, The aim was to expose an appropriate raw material to develop epoxy-fixed pericardial heterografts as alternatives to the glutaraldehyde-fixed prostheses for clinical applications, It was found that the thermal stability, wettability, surface tension, and resistance against collagenase degradation of the pericardia from four species, both before and after chemical modification, were comparable. However, the bovine pericardium appeared to have a better mechanical strength than the other species, Therefore, if mechanical strength is an issue to be taken into account for assessing the performance of pericardial heterografts, the bovine pericardium seems to be the choice of raw material for constructing the prostheses.
Relation:	JOURNAL OF THE CHINESE INSTITUTE OF CHEMICAL ENGINEERS
Appears in Collections:	[National Central University Department of Chemical & Materials Engineering] journal & Dissertation

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