Time-Dependent Block of Ultrarapid-Delayed Rectifier K+ Currents by Aconitine, a Potent Cardiotoxin, in Heart-Derived H9c2 Myoblasts and in Neonatal Rat Ventricular Myocytes

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Title:	Time-Dependent Block of Ultrarapid-Delayed Rectifier K+ Currents by Aconitine, a Potent Cardiotoxin, in Heart-Derived H9c2 Myoblasts and in Neonatal Rat Ventricular Myocytes
Authors:	Wang,YJ;Chen,BS;Lin,MW;Lin,AA;Peng,H;Sung,RJ;Wu,SN
Contributors:	生命科學研究所
Keywords:	SENSITIVE POTASSIUM CHANNELS;PITUITARY GH(3) CELLS;SODIUM-CHANNELS;OUTWARD CURRENT;NEURONAL CELLS;EXPRESSION;PHOSPHORYLATION;PROLIFERATION;COMPONENT;CANCER
Date:	2008
Issue Date:	2010-07-07 11:37:48 (UTC+8)
Publisher:	中央大學
Abstract:	Aconitine (ACO), a highly toxic diterpenoid alkaloid, is recognized to have effects on cardiac voltage-gated Na+ channels. However, it remains unknown whether it has any effects on K+ currents. The effects of ACO on ion currents in differentiated clonal c
Relation:	TOXICOLOGICAL SCIENCES
Appears in Collections:	[Graduate Institute of Life Science] journal & Dissertation

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