Identification of the minimum effective dose based on weighted Kaplan-Meier statistics

NCU Institutional Repository > 理學院 > 統計研究所 > 期刊論文 > Item 987654321/51870

請使用永久網址來引用或連結此文件: http://ir.lib.ncu.edu.tw/handle/987654321/51870

題名:	Identification of the minimum effective dose based on weighted Kaplan-Meier statistics
作者:	Chang,YM;Chen,YI
貢獻者:	統計研究所
關鍵詞:	CENSORED SURVIVAL-DATA;TESTING PROCEDURES;INFERENCE;TRIALS
日期:	2011
上傳時間:	2012-03-27 19:08:01 (UTC+8)
出版者:	國立中央大學
摘要:	Testing procedures are considered for identifying the minimum effective dose (MED) in a dose-response study with randomly right-censored survival data, where the MED is defined to be the smallest dose level under study that has survival advantage over the zero dose control. The proposed testing procedures are implemented in a step-down manner together with three different types of weighted Kaplan-Meier statistics. Comparative results of a Monte Carlo error rate and power/bias study for a variety of survival and censoring distributions are then presented and discussed. The application of the proposed procedures is finally illustrated for identifying the MED of the diethylstilbestrol in the treatment of prostate cancer.
關聯:	JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION
顯示於類別:	[統計研究所] 期刊論文

文件中的檔案:

檔案	描述	大小	格式	瀏覽次數
index.html		0Kb	HTML	650	檢視/開啟

在NCUIR中所有的資料項目都受到原著作權保護.

社群 sharing