本研究為使用有刻印的 PMMA 板夾入 PMMA 基板內作為微流道晶片,並置入鍵合溶劑(丙酮、酒精)進行鍵合,觀察其鍵合狀況。因 PMMA 對鍵合溶劑有不同的反應性,並隨著施予鍵合壓力的上升有所變化。因此本次實驗設計為鍵合壓力參數 30N、40N、50N,以酒精、丙酮及其混和溶劑進行鍵合。使用光學顯微鏡觀察微觀結構、並以數位光彈進行應力分析以及使用拉伸試驗觀察其鍵合強度。經實驗發現丙酮對 PMMA 之反應性較酒精強,鍵合能力較佳,但對 PMMA 材料的結構也有較多的破壞,而鍵合壓力的上升直觀的使鍵合強度隨之上升。;In this study, we used a marked PMMA board was sandwiched between PMMA substrates as a micro-channel wafer, and a bonding solvent (acetone, alcohol) was placed for bonding, and the bonding status was observed. PMMA has different reactivity to the bonding solvent and changes with the increase of the bonding pressure applied. Therefore, this experiment is designed for bonding pressure parameters of 30N, 40N, and 50N, and bonding is performed with alcohol, acetone, and their mixed solvents. Observe the microstructure using an optical microscope, perform stress analysis with digital photoelasticity, and observe the bonding strength using the Lashin test. It has been found through experiments that acetone is more reactive to PMMA than alcohol and has better bonding ability, but it also has more damage to the structure of PMMA materials, and the increase in bonding force intuitively increases the bonding strength.