三甲基溴矽烷(bromotrimethylsilane)促進鄰芳乙炔基芐醇((oarylethynyl) benzyl)生成溴取代的2-芳基苯乙酮(brominated 2-aryl acetophenone)，並透過追蹤1H NMR 探討了其反應機制，此方法不含 金屬且操作簡單。 利用該方法我們製備了20 種不同的衍生物，其中產率最高可達 到99%，此外，我們還嘗試做了一些應用，進一步證明了該方法的實 用性。;A metal-free and operationally simple protocol has been developed to prepare 2-Aryl acetophenone derivatives from readily available (o- Arylethynyl)benzyl alcohols under an acid condition. The reaction is scalable for 20 examples and the yields up to 99%, further applications demonstrated the practicability of the protocol.
