開環聚合反應是由環狀單體透過有機催化劑或有機金屬催化劑與起始劑經由加成反應成為線性或環狀聚合物 ; 是合成可生物降解性聚合物的一種有效方法。在配位基選擇上，由於醯胺類化合物其結構含有NH鍵、C=O鍵，易與中心金屬產生交互作用；亞胺類化合物其結構中N的電子對能調節中心金屬電子環境，因此本實驗合成出草醯胺結構、吡啶亞胺結構的配位基。實驗為使用不同的鈉醇鹽與配位基形成鈉金屬錯合物，並添加醇類作為起始劑，應用於環酯類單體ε-己內酯 (ε-CL)、L-丙交酯 (L-LA) 和δ-戊内酯 (δ-VL) 的開環聚合。根據實驗結果顯示，草醯胺結構配位基與叔丁醇鈉形成的錯合物，若不添加起始劑時，雖然會使單體開環聚合，但其分子量分布度較差 (Ð = 2.89)；當添加醇類為起始劑反應時，對三種單體都有良好的聚合轉換速率，且分子量分布度較好 (ε-CL conv.= 99% in 2 min，Ð = 1.28)。吡啶亞胺結構的配位基與叔丁醇鈉形成的錯合物，在ε-CL、L-LA單體的開環聚合中表現出較高的反應活性 (ε-CL conv.= 93% in 1 min、L-LA conv.= 96% in 1 min)。;Ring-opening polymerization is one type of polymerization reactions using cyclic molecules as its monomers catalyzed by organic or organometallic compounds with or without alcohol initiators to form linear or cyclic polymers. It is an effective method for synthesizing biodegradable polymers. In this study, I synthesized oxamide ligands and Schiff base ligands. Oxamide ligands contain N-H bond and C=O bond functional groups ; Schiff base ligands contain one lone electron pair of the nitrogen atom. Both ligands are easy to interact with the central metal. This experiment used different sodium salts and alcohol initiators as experimental conditions in ring-opening polymerization of ε-caprolactone (ε-CL), L-lactide (L-LA) and δ-valerolactone (δ-VL). According to the experimental results, if initiator is not added with the oxamide ligands, the dispersity is worse (Ð = 2.89) than adding initiator (ε-CL conv.= 99% in 2 min, Ð = 1.28). Schiff base ligands exhibited high reactivity in the ring-opening polymerization of ε-CL and L-LA monomers (ε-CL conv.= 99% in 2 min, Ð = 1.28).
