| DC 欄位 |
值 |
語言 |
| DC.contributor | 化學學系 | zh_TW |
| DC.creator | 王偉益 | zh_TW |
| DC.creator | WEI-YI Wang | en_US |
| dc.date.accessioned | 2018-8-22T07:39:07Z | |
| dc.date.available | 2018-8-22T07:39:07Z | |
| dc.date.issued | 2018 | |
| dc.identifier.uri | http://ir.lib.ncu.edu.tw:88/thesis/view_etd.asp?URN=105223036 | |
| dc.contributor.department | 化學學系 | zh_TW |
| DC.description | 國立中央大學 | zh_TW |
| DC.description | National Central University | en_US |
| dc.description.abstract | 以肌醇(myo-inositol)作為起始物，與同時作為保護基及掌性輔助劑的右旋樟腦(D-camphor)反應得到單一的非鏡像異構物56，經由選擇性去氧、以疊氮化鈉(sodium azide)作為親核試劑進行SN2反應生成碳氮鍵、Staudinger還原反應等步驟，得到其關鍵中心脫氧胺基鯊肌醇(2-deoxy-scyllo-inosamine)此種結構，最後再經由一系列反應得到Nabscessin A及Nabscessin B。 | zh_TW |
| dc.description.abstract | Nabscessin A and Nabscessin B were prepared from commercial available myo-inositol. Treating myo-inositol with protective reagent D- camphor, serving as chiral auxiliary simultaneously, got the diastereomeric pure compound 56. Subsequent transformatios, including selective deoxygenation, amino group formation, etc, provided the key 2-deoxy-scyllo-inosamine core. Finally we completed the synthesis through a series of reaction. | en_US |
| DC.subject | 肌醇 | zh_TW |
| DC.subject | 右旋樟腦 | zh_TW |
| DC.subject | Nabscessin A | zh_TW |
| DC.subject | Nabscessin B | zh_TW |
| DC.subject | Nabscessin A | en_US |
| DC.subject | Nabscessin B | en_US |
| DC.subject | inositol | en_US |
| DC.subject | D-camphor | en_US |
| DC.title | ent-Nabscessin A 及 Nabscessin B 之合成研究 | zh_TW |
| dc.language.iso | zh-TW | zh-TW |
| DC.type | 博碩士論文 | zh_TW |
| DC.type | thesis | en_US |
| DC.publisher | National Central University | en_US |