| dc.description.abstract | Three-dimensional bioprinting combines the advantages of tissue engineering and additive manufacturing technology to make biological scaffolds or artificial tissue and organs, solving problems such as human tissue or the transplantation and repairing of organ. Among them, due to the introduction of additive manufacturing technology, it is more efficient to make porous and complex contoured biological scaffolds. In order to improve the level of the working platform and shorten the levelling time, this study is going to develop a bio-printer with automatic levelling and the material printed by micro-valve inkjet. In order to prevent cell damage, it possesses rapid deposition and low pre-pressure. In addition, it enhances temperature control ability, provides a better printing environment to manufacture biological scaffolds.
The bio-printer system developed by this study includes motion control module, temperature cycling control module, micro valve inkjet module and distance sensing module. The newly designed automatic leveling platform is classified into motion control module, and has a three-axis linear motor as synchronous drive. In addition to the main function is using automatic leveling as the replacement of manual adjustment, it also contains the control of working platform lifting, and develop the user interface of C# environment to let the operation convenient for user.
It is found that the method is feasible by the actual use of microvalve inkjet printing results, and has the advantages of non-contact printing, no need to consider the collision between needle and scaffold, as well as the problem of material adhesion. The printing quality can be improved by optimizing the printing parameters; furthermore, for comprehensive comparison of the printed results by different parameters is made, and print the high-level scaffold ultimately. | en_US |