博碩士論文 89223022 完整後設資料紀錄

DC 欄位	值	語言
DC.contributor	化學學系	zh_TW
DC.creator	戴志和	zh_TW
DC.creator	Jr-He Dai	en_US
dc.date.accessioned	2002-7-22T07:39:07Z
dc.date.available	2002-7-22T07:39:07Z
dc.date.issued	2002
dc.identifier.uri	http://ir.lib.ncu.edu.tw:88/thesis/view_etd.asp?URN=89223022
dc.contributor.department	化學學系	zh_TW
DC.description	國立中央大學	zh_TW
DC.description	National Central University	en_US
dc.description.abstract	第一章 在Merrifield樹脂接上一Thiophenol之官能基。選擇採用Alkylation、Addition或Mitsunobu reaction等方法接上不同的substrates並進行所需要的反應，接著利用氧化、Pummer Rearrange與TEA或NaBH4斷裂之三步驟系統反應將產物從樹脂上斷裂下來，最終可以得到Alcohols、Aldehydes、Diols、Peptides…等產物。 第二章 以第二代Hydroxybenzotriazoles系列與第三代Hydroxyphenyltriazine系列產品的結構做為基礎，設計一個新型的UV Absorber，期望可以開發出具有較佳性質與較低生產成本之產品。	zh_TW
dc.description.abstract	Chapter I A new and versatile Safety-Catch linker for solid phase syntheses is described. The phenol group of trityl protected thiophenol was first attached and then after deprotect it, the thiol group of the Safety-Catch linker was alkylated to various of substrates. A the end of each solid phase syntheses sequence, these linkers were activated and cleaved by pummer rearrangement to produce alcohols or aldehydes under two different cleavage conditions. Chapter II We haved designed and synthesized a series of novel UV asorbers based on known commerical products of Hydroxybenzotriazoles and Hydroxyphenyltriazines. These new UV asorbers are expected to have better quality and cost less.	en_US
DC.subject	鍵鏈劑	zh_TW
DC.subject	安全閥	zh_TW
DC.subject	藥物合成	zh_TW
DC.subject	組合化學	zh_TW
DC.subject	紫外線吸收劑	zh_TW
DC.subject	safety catch	en_US
DC.subject	combinatorial chemistry	en_US
DC.subject	linker	en_US
DC.subject	uv asorber	en_US
DC.title	一、開發組合式藥物合成所需具安全閥(Safety Catch)之鍵鏈劑 二、開發新型紫外光吸收劑	zh_TW
dc.language.iso	zh-TW	zh-TW
DC.title	1.A new and versatile Safety-Catch linker for solid phase syntheses2.Design and syntheses of a series of novel UV asorbers	en_US
DC.type	博碩士論文	zh_TW
DC.type	thesis	en_US
DC.publisher	National Central University	en_US