DC 欄位 值 語言 DC.contributor 電機工程學系 zh_TW DC.creator 陳佳俊 zh_TW DC.creator Chia-chun Chen en_US dc.date.accessioned 2013-8-26T07:39:07Z dc.date.available 2013-8-26T07:39:07Z dc.date.issued 2013 dc.identifier.uri http://ir.lib.ncu.edu.tw:88/thesis/view_etd.asp?URN=995201076 dc.contributor.department 電機工程學系 zh_TW DC.description 國立中央大學 zh_TW DC.description National Central University en_US dc.description.abstract 心血管系統模型的用途十分廣泛，常運用在臨床診斷、藥品測試和醫療儀器開發等方面。本研究的目的是以生理資料為基礎建構心血管系統模型，根據生理文獻上的資料將模型中的血管阻力與順應性以等效的電路元件來模擬，進行多個週期的模擬及觀察模擬的結果。除此之外，在模型中加入神經系統的調控，使模型可模擬交感神經對心室體積與血管阻抗的監控，以達到維持血壓的功能。除了模擬正常情況下的生理現象，我們也做了其他兩種病態的模擬，此兩種病態分別為主動脈瓣膜狹窄與僧帽瓣膜狹窄。從結果顯示本論文的心血管系統模型可以成功模擬出正常時的右心臟、左心臟和其它部位血管的血壓以及瓣膜異常的病理特徵，比較模擬結果和文獻與生理書上的資料 ，驗證系統模型在模擬上的可行性。 zh_TW dc.description.abstract The cardiovascular system models could be widely used in clinical diagnosis, drug testing, development of medical instrumentation, and so on. The purpose of this study is to build a cardiovascular system model based on the physiological data. The equivalent circuit elements were used to model the resistance and compliance of the vascular system, implement the multi-cycle simulation, and observe the simulated results. Furthermore, the neural control was added to regulate simulation of the model. This neural control provided simulation of the autonomic regulation on the blood pressure through the ventricular volume and vascular resistance. In addition to the simulation of normal condition, the model was used to simulate two pathological conditions, i.e., aortic and mitral valve stenoses. Comparison between the results of our simulation and previous literature studies, our results showed that this cardiovascular system model was capable to simulate normal blood pressure of right heart, left heart, other parts of the blood vessels, and pathological features of valve stenosis and indicated its feasibility as a cardiovascular system model. en_US DC.subject 心血管系統模型 zh_TW DC.subject 模擬 zh_TW DC.subject 主動脈瓣膜狹窄 zh_TW DC.subject 僧帽瓣膜狹窄 zh_TW DC.subject Cardiovascular System en_US DC.subject Simulation en_US DC.subject Aortic Stenosis en_US DC.subject Mitral Stenosis en_US DC.title 以生理資料為基礎的心血管系統模型之建構 zh_TW dc.language.iso zh-TW zh-TW DC.title Cardiovascular system modeling based on the physiology data en_US DC.type 博碩士論文 zh_TW DC.type thesis en_US DC.publisher National Central University en_US