博碩士論文 101223024 詳細資訊




以作者查詢圖書館館藏 以作者查詢臺灣博碩士 以作者查詢全國書目 勘誤回報 、線上人數:18 、訪客IP:3.94.21.209
姓名 王劭群(Shao-Chun Wang)  查詢紙本館藏   畢業系所 化學學系
論文名稱 以水相系統合成類沸石咪唑骨架材料(ZIF-90)及其在生物酵素催化上的應用
(Water-Based Synthesis of Zeolitic Imidazolate Framework-90 (ZIF-90) with a Controllable Particle Size and its Application in Biocatalysis)
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摘要(中) 類沸石咪唑骨架材料是屬於金屬有機骨架材料的範疇,其主要是利用咪唑或是咪唑衍生
物(Im)當作有機配位體與鋅、鈷等過渡金屬(M)鍵結所形成的聚合物,結構中Im-M-Im的
鍵結角度約為145度,與天然沸石中Si-O-Si的鍵結角度大約相同,故被稱之為類沸石咪
唑骨架材料,目前主要有儲存氣體、分離混和氣體、非均相催化和藥物載體的應用。本
論文所介紹的類沸石咪唑骨架材料-90(Zeolitic Imidazolate Framework-90;ZIF-90)
已有報導指出此材料易於官能基化的特點,並具有極為優異的水熱穩定性。然而,目前
合成ZIF-90之方法大多需使用有機溶劑(如DMF),但若大量製造ZIF-90時,所產生的廢
液將對於環境造成負擔。為了符合綠色化學之製程,此研究中,我們提供了一種於水相
系統中製備ZIF-90之方法,能夠製造出粒徑大小一致且尺寸具有均一性的ZIF-90。
摘要(英) In zeolitic imidazolate frameworks (ZIFs), a subclass of metal–organic
frameworks (MOFs), metal ions such as Zn2+ and Co2+ are linked through the
nitrogen atoms of the deprotonated imidazolate to form neutral frameworks
and provide a tunable crystalline structure and porosity and a high internal
surface area. Additionally, the M–Im–M angle is similar to that of the
Si–O–Si angle (145o) preferred in zeolites. This fact has led to the
synthesis of a large number of ZIFs with zeolite-type tetrahedral
topologies. Therefore, ZIFs have recently attracted considerable attention
for applications in gas storage, separation of small molecules,
heterogeneous catalysis, sensors and drug delivery.
Zeolitic Imidazolate Framework-90 (ZIF-90), the main character of the
thesis, was reported to have high thermal and solvent stability. However,
most of the strategies reported so far on the synthesis of ZIF-90 have
involved the use of solvents, such as dimethyl formamide (DMF), methanol, or
other organic solvents which are also expensive, in addition to their
environmental concerns, such as toxicity, high-pollution, and waste
treatment issues. Herein, we report for the first time, a rapid and
eco-friendly strategy for the synthesis of ZIF-90 under aqueous conditions,
and thus, ZIF-90 having uniform particle sizes can be produced.
關鍵字(中) ★ 微孔洞材料
★ 類沸石咪唑骨架材料
★ 固定化酵素
★ 金屬有機骨架材料
★ 環保
關鍵字(英) ★ Microporous material
★ Zeolitic imidazolate framework
★ Immobolized enzyme
★ Metal-organic framework
★ Environmental friendly
論文目次 中文摘要 A
Abstract C
第一章 緒論 1
1-1 金屬有機骨架材料 1
1-2 類沸石咪唑骨架材料 3
1-3 類沸石咪唑骨架材料-90 5
1-4 研究動機與目的 6
第二章 實驗部分 8
2-1 實驗藥品 8
2-2 實驗儀器與方法 8
2-2-1 X射線粉末繞射儀 (Powder X-ray Diffractometer,XRD) 8
2-2-2 場發掃描式電子顯微鏡 (Field-emission Scanning Electron Microscope,SEM) 10
2-2-3 等溫氮氣吸/脫附儀 (Accelerated Surface Area and Porosimetry system,ASAP) 11
2-2-4 熱重分析儀 (Thermogravimetric Analyzer,TGA) 13
2-2-5 傅立葉轉換紅外線光譜儀 (Fourier Transform Infrared Spectrometer,FT-IR) 14
2-2-6 固態核磁共振儀 (Solid State Nuclear Magnetic Resonance,SSNMR) 15
2-3類沸石咪唑骨架材料的合成 16
2-3-1 純水相系統合成類沸石咪唑骨架材料-90 16
2-3-2醇水混和系統合成類沸石咪唑骨架奈米材料-90 17
第三章 結果與討論 19
3-1純水相系統合成類沸石咪唑骨架材料-90 19
3-1-1 類沸石咪唑骨架材料-90(ZIF-90)的鑑定 19
3-1-2 不同濃度的乙烯基吡咯烷酮水溶液對ZIF-90合成結果之討論 22
3-1-3 不同的莫耳當量比(Zn/ICA)對ZIF-90合成結果之討論 23
3-2 醇水混和系統合成類沸石咪唑骨架奈米材料-90 24
第四章 結論 28
第五章 緒論 29
5-1 固定化酵素(Immobilized Enzyme) 29
5-2 過氧化氫酶(Catalase) 32
5-3 蛋白酶K(Proteinase K) 35
5-4 研究動機與目的 37
第六章 實驗部分 40
6-1 實驗藥品 40
6-2 實驗儀器與方法 41
6-2-1 紫外光可見光分光光譜儀 (UV/VIS Spectophotometer) 41
6-2-2 十二烷基硫酸鈉聚丙烯醯胺膠體電泳 (SDS-PAGE) 42
6-2-3 偵測蛋白質的濃度(Bradford Assay) 46
6-2-4 偵測過氧化氫水溶液之濃度 (Ferrous Oxidation in Xylenol orange assay, FOX assay) 47
6-3 類沸石咪唑骨架-90包覆過氧化氫酶材料(CAT@ZIF-90)的合成 49
6-4 類沸石咪唑骨架-90包覆過氧化氫酶材料(CAT@ZIF-90)中蛋白質的含量 50
6-5 類沸石咪唑骨架-90包覆過氧化氫酶材料(CAT@ZIF-90)的活性測試 50
6-5添加蛋白酶(Proteinase K)的抑制測試 51
第七章 結果與討論 52
7-1 類沸石咪唑骨架材料-90包覆過氧化氫酶(CAT@ZIF-90)的鑑定 52
7-2 類沸石咪唑骨架材料-90包覆過氧化氫酶材料(CAT@ZIF-90)的活性 55
7-3 添加蛋白酶(Proteinase K)的結果與討論 56
第八章 結論 57
第九章 參考文獻 58
第十章 附錄 65
參考文獻 1. Yaghi, O. M.; O′Keeffe, M.; Ockwig, N. W.; Chae, H. K.; Eddaoudi, M.; Kim, J., Reticular synthesis and the design of new materials. Nature 2003, 423 (6941), 705-714.
2. Furukawa, H.; Cordova, K. E.; O’Keeffe, M.; Yaghi, O. M., The Chemistry and Applications of Metal-Organic Frameworks. Science 2013, 341 (6149).
3. Getman, R. B.; Bae, Y.-S.; Wilmer, C. E.; Snurr, R. Q., Review and Analysis of Molecular Simulations of Methane, Hydrogen, and Acetylene Storage in Metal–Organic Frameworks. Chem. Rev. 2011, 112 (2), 703-723.
4. Suh, M. P.; Park, H. J.; Prasad, T. K.; Lim, D.-W., Hydrogen Storage in Metal–Organic Frameworks. Chem. Rev. 2011, 112 (2), 782-835.
5. Li, J.-R.; Sculley, J.; Zhou, H.-C., Metal–Organic Frameworks for Separations. Chem. Rev. 2011, 112 (2), 869-932.
6. Yoon, M.; Srirambalaji, R.; Kim, K., Homochiral Metal–Organic Frameworks for Asymmetric Heterogeneous Catalysis. Chem. Rev. 2011, 112 (2), 1196-1231.
7. Bétard, A.; Fischer, R. A., Metal–Organic Framework Thin Films: From Fundamentals to Applications. Chem. Rev. 2011, 112 (2), 1055-1083.
8. Kreno, L. E.; Leong, K.; Farha, O. K.; Allendorf, M.; Van Duyne, R. P.; Hupp, J. T., Metal–Organic Framework Materials as Chemical Sensors. Chem. Rev. 2011, 112 (2), 1105-1125.
9. Horcajada, P.; Gref, R.; Baati, T.; Allan, P. K.; Maurin, G.; Couvreur, P.; Férey, G.; Morris, R. E.; Serre, C., Metal–Organic Frameworks in Biomedicine. Chem. Rev. 2011, 112 (2), 1232-1268.
10. Yoon, M.; Suh, K.; Natarajan, S.; Kim, K., Proton Conduction in Metal–Organic Frameworks and Related Modularly Built Porous Solids. Angew. Chem. Int. Ed. 2013, 52 (10), 2688-2700.
11. Li, S.-L.; Xu, Q., Metal-organic frameworks as platforms for clean energy. Energy Environ. Sci. 2013, 6 (6), 1656-1683.
12. Hoskins, B. F.; Robson, R., Design and construction of a new class of scaffolding-like materials comprising infinite polymeric frameworks of 3D-linked molecular rods. A reappraisal of the zinc cyanide and cadmium cyanide structures and the synthesis and structure of the diamond-related frameworks [N(CH3)4][CuIZnII(CN)4] and CuI[4,4′,4′′,4′′′-tetracyanotetraphenylmethane]BF4.xC6H5NO2. J. Am. Chem. Soc. 1990, 112 (4), 1546-1554.
13. Rabenau, A., The Role of Hydrothermal Synthesis in Preparative Chemistry. Angew. Chem., Int. Ed. Engl. 1985, 24 (12), 1026-1040.
14. Klinowski, J.; Almeida Paz, F. A.; Silva, P.; Rocha, J., Microwave-Assisted Synthesis of Metal-Organic Frameworks. Dalton Trans. 2011, 40 (2), 321-330.
15. Ameloot, R.; Stappers, L.; Fransaer, J.; Alaerts, L.; Sels, B. F.; De Vos, D. E., Patterned Growth of Metal-Organic Framework Coatings by Electrochemical Synthesis. Chem. Mater. 2009, 21 (13), 2580-2582.
16. Pichon, A.; Lazuen-Garay, A.; James, S. L., Solvent-free synthesis of a microporous metal-organic framework. CrystEngComm 2006, 8 (3), 211-214.
17. Qiu, L.-G.; Li, Z.-Q.; Wu, Y.; Wang, W.; Xu, T.; Jiang, X., Facile synthesis of nanocrystals of a microporous metal-organic framework by an ultrasonic method and selective sensing of organoamines. Chem. Commun. 2008, (31), 3642-3644.
18. Stock, N.; Biswas, S., Synthesis of Metal-Organic Frameworks (MOFs): Routes to Various MOF Topologies, Morphologies, and Composites. Chem. Rev. 2011, 112 (2), 933-969.
19. Banerjee, R.; Phan, A.; Wang, B.; Knobler, C.; Furukawa, H.; O′Keeffe, M.; Yaghi, O. M., High-Throughput Synthesis of Zeolitic Imidazolate Frameworks and Application to CO2 Capture. Science 2008, 319 (5865), 939-943.
20. Phan, A.; Doonan, C. J.; Uribe-Romo, F. J.; Knobler, C. B.; O’Keeffe, M.; Yaghi, O. M., Synthesis, Structure, and Carbon Dioxide Capture Properties of Zeolitic Imidazolate Frameworks. Acc. Chem. Res. 2009, 43 (1), 58-67.
21. Park, K. S.; Ni, Z.; Côté, A. P.; Choi, J. Y.; Huang, R.; Uribe-Romo, F. J.; Chae, H. K.; O’Keeffe, M.; Yaghi, O. M., Exceptional chemical and thermal stability of zeolitic imidazolate frameworks. Proc. Natl. Acad. Sci. 2006, 103 (27), 10186-10191.
22. Pérez-Pellitero, J.; Amrouche, H.; Siperstein, F. R.; Pirngruber, G.; Nieto-Draghi, C.; Chaplais, G.; Simon-Masseron, A.; Bazer-Bachi, D.; Peralta, D.; Bats, N., Adsorption of CO2, CH4, and N2 on Zeolitic Imidazolate Frameworks: Experiments and Simulations. Chem. Eur. J. 2010, 16 (5), 1560-1571.
23. Pan, Y.; Lai, Z., Sharp separation of C2/C3 hydrocarbon mixtures by zeolitic imidazolate framework-8 (ZIF-8) membranes synthesized in aqueous solutions. Chem. Commun. 2011, 47 (37), 10275-10277.
24. Song, Q.; Nataraj, S. K.; Roussenova, M. V.; Tan, J. C.; Hughes, D. J.; Li, W.; Bourgoin, P.; Alam, M. A.; Cheetham, A. K.; Al-Muhtaseb, S. A.; Sivaniah, E., Zeolitic imidazolate framework (ZIF-8) based polymer nanocomposite membranes for gas separation. Energy Environ. Sci. 2012, 5 (8), 8359-8369.
25. Wu, H.; Zhou, W.; Yildirim, T., Hydrogen Storage in a Prototypical Zeolitic Imidazolate Framework-8. J. Am. Chem. Soc. 2007, 129 (17), 5314-5315.
26. Han, S. S.; Choi, S.-H.; Goddard, W. A., Improved H2 Storage in Zeolitic Imidazolate Frameworks Using Li+, Na+, and K+ Dopants, with an Emphasis on Delivery H2 Uptake. The Journal of Physical Chemistry C 2011, 115 (8), 3507-3512.
27. Kuo, C.-H.; Tang, Y.; Chou, L.-Y.; Sneed, B. T.; Brodsky, C. N.; Zhao, Z.; Tsung, C.-K., Yolk–Shell Nanocrystal@ZIF-8 Nanostructures for Gas-Phase Heterogeneous Catalysis with Selectivity Control. J. Am. Chem. Soc. 2012, 134 (35), 14345-14348.
28. Wee, L. H.; Lescouet, T.; Ethiraj, J.; Bonino, F.; Vidruk, R.; Garrier, E.; Packet, D.; Bordiga, S.; Farrusseng, D.; Herskowitz, M.; Martens, J. A., Hierarchical Zeolitic Imidazolate Framework-8 Catalyst for Monoglyceride Synthesis. ChemCatChem 2013, 5 (12), 3562-3566.
29. Chen, E.-X.; Yang, H.; Zhang, J., Zeolitic Imidazolate Framework as Formaldehyde Gas Sensor. Inorg. Chem. 2014, 53 (11), 5411-5413.
30. Zhuang, J.; Kuo, C.-H.; Chou, L.-Y.; Liu, D.-Y.; Weerapana, E.; Tsung, C.-K., Optimized Metal–Organic-Framework Nanospheres for Drug Delivery: Evaluation of Small-Molecule Encapsulation. ACS Nano 2014, 8 (3), 2812-2819.
31. Vasconcelos, I. B.; Silva, T. G. d.; Militao, G. C. G.; Soares, T. A.; Rodrigues, N. M.; Rodrigues, M. O.; Costa, N. B. d.; Freire, R. O.; Junior, S. A., Cytotoxicity and slow release of the anti-cancer drug doxorubicin from ZIF-8. RSC Adv. 2012, 2 (25), 9437-9442.
32. Morris, W.; Doonan, C. J.; Furukawa, H.; Banerjee, R.; Yaghi, O. M., Crystals as Molecules: Postsynthesis Covalent Functionalization of Zeolitic Imidazolate Frameworks. J. Am. Chem. Soc. 2008, 130 (38), 12626-12627.
33. Raveendran, P.; Ikushima, Y.; Wallen, S. L., Polar Attributes of Supercritical Carbon Dioxide. Acc. Chem. Res. 2005, 38 (6), 478-485.
34. Bae, T.-H.; Lee, J. S.; Qiu, W.; Koros, W. J.; Jones, C. W.; Nair, S., A High-Performance Gas-Separation Membrane Containing Submicrometer-Sized Metal–Organic Framework Crystals. Angew. Chem. Int. Ed. 2010, 49 (51), 9863-9866.
35. Yu, L.-Q.; Yang, C.-X.; Yan, X.-P., Room temperature fabrication of post-modified zeolitic imidazolate framework-90 as stationary phase for open-tubular capillary electrochromatography. J. Chromatogr. A 2014, 1343 (0), 188-194.
36. Pan, Y.; Liu, Y.; Zeng, G.; Zhao, L.; Lai, Z., Rapid synthesis of zeolitic imidazolate framework-8 (ZIF-8) nanocrystals in an aqueous system. Chem. Commun. 2011, 47 (7), 2071-2073.
37. Gross, A. F.; Sherman, E.; Vajo, J. J., Aqueous room temperature synthesis of cobalt and zinc sodalite zeolitic imidizolate frameworks. Dalton Trans. 2012, 41 (18), 5458-5460.
38. Gaumet, M.; Vargas, A.; Gurny, R.; Delie, F., Nanoparticles for drug delivery: The need for precision in reporting particle size parameters. Eur. J. Pharm. Biopharm. 2008, 69 (1), 1-9.
39. Brown, A. J.; Johnson, J. R.; Lydon, M. E.; Koros, W. J.; Jones, C. W.; Nair, S., Continuous Polycrystalline Zeolitic Imidazolate Framework-90 Membranes on Polymeric Hollow Fibers. Angew. Chem. Int. Ed. 2012, 51 (42), 10615-10618.
40. Jauncey, G. E. M., The Scattering of X-Rays and Bragg′s Law. Proc. Natl. Acad. Sci. 1924, 10 (2), 57-60.
41. Sing, K. S. W.; Everett, D. H.; Haul, R. A. W.; Moscou, L.; Pierotti, R. A.; Rouquerol, J.; Siemieniewska, T., Reporting Physisorption Data for Gas/Solid Systems with Special Reference to the Determination of Surface Area and Porosity. Pure Appl. Chem. 1985, 57 (4), 17.
42. Brunauer, S.; Emmett, P. H.; Teller, E., Adsorption of Gases in Multimolecular Layers. J. Am. Chem. Soc. 1938, 60 (2), 309-319.
43. Langmuir, I., The Adsorption of Gases on Plane Surfaces of Glass, Mica and Platinum. J. Am. Chem. Soc. 1918, 40 (9), 1361-1403.
44. Andrew, E. R.; Bradbury, A.; Eades, R. G., Nuclear Magnetic Resonance Spectra from a Crystal rotated at High Speed. Nature 1958, 182 (4650), 1659-1659.
45. Pastoriza-Santos, I.; Liz-Marzán, L. M., Formation of PVP-Protected Metal Nanoparticles in DMF. Langmuir 2002, 18 (7), 2888-2894.
46. Nune, S. K.; Thallapally, P. K.; Dohnalkova, A.; Wang, C.; Liu, J.; Exarhos, G. J., Synthesis and properties of nano zeolitic imidazolate frameworks. Chem. Commun. 2010, 46 (27), 4878-4880.
47. Kida, K.; Okita, M.; Fujita, K.; Tanaka, S.; Miyake, Y., Formation of high crystalline ZIF-8 in an aqueous solution. CrystEngComm 2013, 15 (9), 1794-1801.
48. Messing, R. A., Chapter 1 - INTRODUCTION AND GENERAL HISTORY OF IMMOBILIZED ENZYMES. In Immobilized Enzymes for Industrial Reactors, Messing, R. A., Ed. Academic Press: 1975, pp 1-10.
49. Datta, S.; Christena, L. R.; Rajaram, Y., Enzyme immobilization: an overview on techniques and support materials. 3 Biotech 2013, 3 (1), 1-9.
50. Brady, D.; Jordaan, J., Advances in enzyme immobilisation. Biotechnol. Lett 2009, 31 (11), 1639-1650.
51. Chen, Y.; Lykourinou, V.; Hoang, T.; Ming, L.-J.; Ma, S., Size-Selective Biocatalysis of Myoglobin Immobilized into a Mesoporous Metal–Organic Framework with Hierarchical Pore Sizes. Inorg. Chem. 2012, 51 (17), 9156-9158.
52. Wong, L. S.; Thirlway, J.; Micklefield, J., Direct Site-Selective Covalent Protein Immobilization Catalyzed by a Phosphopantetheinyl Transferase. J. Am. Chem. Soc. 2008, 130 (37), 12456-12464.
53. Hsieh, H.-J.; Liu, P.-C.; Liao, W.-J., Immobilization of invertase via carbohydrate moiety on chitosan to enhance its thermal stability. Biotechnol. Lett 2000, 22 (18), 1459-1464.
54. Ispas, C.; Sokolov, I.; Andreescu, S., Enzyme-functionalized mesoporous silica for bioanalytical applications. Anal. Bioanal. Chem. 2009, 393 (2), 543-554.
55. Bernfeld, P.; Wan, J., Antigens and Enzymes Made Insoluble by Entrapping Them into Lattices of Synthetic Polymers. Science 1963, 142 (3593), 678-679.
56. Shen, Q.; Yang, R.; Hua, X.; Ye, F.; Zhang, W.; Zhao, W., Gelatin-templated biomimetic calcification for β-galactosidase immobilization. Process Biochem. 2011, 46 (8), 1565-1571.
57. Wang, Z.-G.; Wan, L.-S.; Liu, Z.-M.; Huang, X.-J.; Xu, Z.-K., Enzyme immobilization on electrospun polymer nanofibers: An overview. J. Mol. Catal. B: Enzym. 2009, 56 (4), 189-195.
58. Wen, H.; Nallathambi, V.; Chakraborty, D.; Calabrese Barton, S., Carbon fiber microelectrodes modified with carbon nanotubes as a new support for immobilization of glucose oxidase. Microchim Acta 2011, 175 (3-4), 283-289.
59. Kim, J.; Jia, H.; Wang, P., Challenges in biocatalysis for enzyme-based biofuel cells. Biotechnol. Adv. 2006, 24 (3), 296-308.
60. Halliwell, B.; Gutteridge, J. M. C., The definition and measurement of antioxidants in biological systems. Free Radical Biol. Med. 1995, 18 (1), 125-126.
61. Valko, M.; Leibfritz, D.; Moncol, J.; Cronin, M. T. D.; Mazur, M.; Telser, J., Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 2007, 39 (1), 44-84.
62. BLOKHINA, O.; VIROLAINEN, E.; FAGERSTEDT, K. V., Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review. Ann. Bot. 2003, 91 (2), 179-194.
63. MatÉs, J. M.; Pérez-Gómez, C.; De Castro, I. N., Antioxidant enzymes and human diseases. Clin. Biochem. 1999, 32 (8), 595-603.
64. Catalase: Physical and chemical properties, mechanism of catalysis, and physiological role. 1970; Vol. 50, p 319-375.
65. Fita, I.; Rossmann, M. G., The NADPH binding site on beef liver catalase. Proc. Natl. Acad. Sci. 1985, 82 (6), 1604-1608.
66. Chance, B., EFFECT OF pH UPON THE REACTION KINETICS OF THE ENZYME-SUBSTRATE COMPOUNDS OF CATALASE. J. Biol. Chem. 1952, 194 (2), 471-481.
67. Ebeling, W.; Hennrich, N.; Klockow, M.; Metz, H.; Orth, H. D.; Lang, H., Proteinase K from Tritirachium album Limber. Eur. J. Biochem. 1974, 47 (1), 91-97.
68. Edgar, K.; Uwe, F., Proteinase K from the Mold Tritirachium album Limber. Specificity and Mode of Action. In Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1976; Vol. 357, p 937.
69. La Claire, J., II; Herrin, D., Co-isolation of high-quality DNA and RNA from coenocytic green algae. Plant Mol. Biol. Rep. 1997, 15 (3), 263-272.
70. Holm, C.; Meeks-Wagner, D. W.; Fangman, W. L.; Botstein, D., A rapid, efficient method for isolating DNA from yeast. Gene 1986, 42 (2), 169-173.
71. Petsch, D.; Deckwer, W. D.; Anspach, F. B., Proteinase K Digestion of Proteins Improves Detection of Bacterial Endotoxins by theLimulusAmebocyte Lysate Assay: Application for Endotoxin Removal from Cationic Proteins. Anal. Biochem. 1998, 259 (1), 42-47.
72. Brdiczka, D.; Krebs, W.; Kloock, P., Localization of enzymes by means of proteases. Biochimica et Biophysica Acta (BBA) - General Subjects 1973, 297 (2), 203-212.
73. Bennion, B. J.; Daggett, V., Protein Conformation and Diagnostic Tests: The Prion Protein. Clin. Chem. 2002, 48 (12), 2105-2114.
74. Jany, K.-D.; Lederer, G.; Mayer, B., Amino acid sequence of proteinase K from the mold Tritirachium album Limber: Proteinase K — a subtilisin-related enzyme with disulfide bonds. FEBS Lett. 1986, 199 (2), 139-144.
75. Burrell, M. M., Enzymes of Molecular Biology. Humana Press: 1993.
76. Müller, A.; Hinrichs, W.; Wolf, W. M.; Saenger, W., Crystal structure of calcium-free proteinase K at 1.5-A resolution. J. Biol. Chem. 1994, 269 (37), 23108-23111.
77. Sun, C.-Y.; Qin, C.; Wang, X.-L.; Yang, G.-S.; Shao, K.-Z.; Lan, Y.-Q.; Su, Z.-M.; Huang, P.; Wang, C.-G.; Wang, E.-B., Zeolitic imidazolate framework-8 as efficient pH-sensitive drug delivery vehicle. Dalton Trans. 2012, 41 (23), 6906-6909.
78. Shieh, F.-K.; Wang, S.-C.; Leo, S.-Y.; Wu, K. C. W., Water-Based Synthesis of Zeolitic Imidazolate Framework-90 (ZIF-90) with a Controllable Particle Size. Chem. Eur. J. 2013, 19 (34), 11139-11142.
79. Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72 (1–2), 248-254.
80. Jiang, Z.-Y.; Woollard, A. C. S.; Wolff, S. P., Hydrogen peroxide production during experimental protein glycation. FEBS Lett. 1990, 268 (1), 69-71.
81. Ou, P.; Wolff, S. P., A discontinuous method for catalase determination at ‘near physiological’ concentrations of H2O2 and its application to the study of H2O2 fluxes within cells. J. Biochem. Bioph. Methods 1996, 31 (1–2), 59-67.
82. Nelson, D. P.; Kiesow, L. A., Enthalpy of decomposition of hydrogen peroxide by catalase at 25° C (with molar extinction coefficients of H2O2 solutions in the UV). Anal. Biochem. 1972, 49 (2), 474-478.
83. Ogura, Y.; Yamazaki, I., Steady-State Kinetics of the Catalase Reaction in the Presence of Cyanide. J. Biochem. 1983, 94 (2), 403-408.
指導教授 謝發坤(Fa-Kuen Shieh) 審核日期 2014-8-14
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