||With the current social changes, many people are generally married late, and psychological factors or environmental pollution may increase the incidence of infertility. At present, infertility has become a global concern. In previous studies, it was pointed out that the causes of infertility were female factors, male factors or unexplained factors. Among them, 25-28% of infertility was caused by unexplained factors. Clinically, the comorbidities between some diseases are significantly correlated and affect each other. In this study, male infertility (ICD9-CM: 606.9) and female infertility (ICD9-CM: 628.9) are used be as the main subject. We used clinical data from Cathay General Hospital (CGH), Landseed Hospital (LSH) and supplemented with National Health Insurance Research Database (NHIRD) to investigate the relationship between infertility and the other diseases and age distribution of infertility in different regions. Also, we analyzed whether medicine used will increase the risk of comorbidity. Our research shows that the prevalence of females in the two hospitals was highest in 2014 from 2008 to 2014, with CGH (0.36%) and LSH (0.52%), and the prevalence of females was higher than that of males. Age distribution showed that there were significant differences between the two hospitals. In the comorbidity of female patients, both hospitals have been shown to have a significant relationship with ovarian, endometriosis, vaginitis and urinary tract infections, while men are associated with urinary tract infections, genital inflammation and other diseases. These results are consistent with past studies. In particular, we have also found contact dermatitis and other eczema in both male and female patients. It may be other causes of infertility, and needs further investigation.|
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