參考文獻 |
1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al.
Cancer incidence and mortality worldwide: sources, methods and major patterns
in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359-86.
2. Mahdavifar N, Ghoncheh M, Pakzad R, Momenimovahed Z, Salehiniya
H. Epidemiology, Incidence and Mortality of Bladder Cancer and their
Relationship with the Development Index in the World. Asian Pac J Cancer Prev.
2016;17(1):381-6.
3. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin.
2019;69(1):7-34.
4. Cohen HT, McGovern FJ. Renal-cell carcinoma. N Engl J Med.
2005;353(23):2477-90.
5. Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger
M, et al. Renal cell carcinoma. Nat Rev Dis Primers. 2017;3:17009.
6. Jonasch E, Gao J, Rathmell WK. Renal cell carcinoma. Bmj.
2014;349:g4797.
7. Nabi S, Kessler ER, Bernard B, Flaig TW, Lam ET. Renal cell carcinoma:
a review of biology and pathophysiology. F1000Res. 2018;7:307.
8. Linehan WM, Ricketts CJ. The Cancer Genome Atlas of renal cell
carcinoma: findings and clinical implications. Nat Rev Urol. 2019;16(9):539-52.
9. Minervini G, Mazzotta GM, Masiero A, Sartori E, Corrà S, Potenza E, et
al. Isoform-specific interactions of the von Hippel-Lindau tumor suppressor
protein. Sci Rep. 2015;5:12605.
10. Gossage L, Eisen T. Alterations in VHL as potential biomarkers in renalcell carcinoma. Nat Rev Clin Oncol. 2010;7(5):277-88.
11. Pritchett TL, Bader HL, Henderson J, Hsu T. Conditional inactivation of
the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread
hyperplastic, inflammatory and fibrotic lesions in the kidney. Oncogene.
2015;34(20):2631-9.
12. Kaplan G, Totsuka A, Thompson P, Akatsuka T, Moritsugu Y, Feinstone
SM. Identification of a surface glycoprotein on African green monkey kidney
cells as a receptor for hepatitis A virus. Embo j. 1996;15(16):4282-96.
13. Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, et al.
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule
containing a novel immunoglobulin domain, is up-regulated in renal cells after
injury. J Biol Chem. 1998;273(7):4135-42.
14. McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et
al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the
linked Tim gene family. Nat Immunol. 2001;2(12):1109-16.
15. de Souza AJ, Oriss TB, O′Malley K J, Ray A, Kane LP. T cell Ig and
mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a
costimulatory signal for T cell activation. Proc Natl Acad Sci U S A.
2005;102(47):17113-8.
16. Ding Q, Yeung M, Camirand G, Zeng Q, Akiba H, Yagita H, et al.
Regulatory B cells are identified by expression of TIM-1 and can be induced40
through TIM-1 ligation to promote tolerance in mice. J Clin Invest.
2011;121(9):3645-56.
17. Ndhlovu LC, Lopez-Vergès S, Barbour JD, Jones RB, Jha AR, Long BR,
et al. Tim-3 marks human natural killer cell maturation and suppresses cellmediated cytotoxicity. Blood. 2012;119(16):3734-43.
18. Nozaki Y, Nikolic-Paterson DJ, Snelgrove SL, Akiba H, Yagita H,
Holdsworth SR, et al. Endogenous Tim-1 (Kim-1) promotes T-cell responses
and cell-mediated injury in experimental crescentic glomerulonephritis. Kidney
Int. 2012;81(9):844-55.
19. Patel J, Bozeman EN, Selvaraj P. Taming dendritic cells with TIM-3:
another immunosuppressive strategy used by tumors. Immunotherapy.
2012;4(12):1795-8.
20. Guo L, Takino T, Endo Y, Domoto T, Sato H. Shedding of kidney injury
molecule-1 by membrane-type 1 matrix metalloproteinase. J Biochem.
2012;152(5):425-32.
21. Santiago C, Ballesteros A, Martínez-Muñoz L, Mellado M, Kaplan GG,
Freeman GJ, et al. Structures of T cell immunoglobulin mucin protein 4 show a
metal-Ion-dependent ligand binding site where phosphatidylserine binds.
Immunity. 2007;27(6):941-51.
22. Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS,
Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that
confers a phagocytic phenotype on epithelial cells. J Clin Invest.
2008;118(5):1657-68.
23. Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyff RH. TIM genes: a
family of cell surface phosphatidylserine receptors that regulate innate and
adaptive immunity. Immunol Rev. 2010;235(1):172-89.
24. Kobayashi N, Karisola P, Peña-Cruz V, Dorfman DM, Jinushi M, Umetsu
SE, et al. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate
uptake of apoptotic cells. Immunity. 2007;27(6):927-40.
25. Ajay AK, Kim TM, Ramirez-Gonzalez V, Park PJ, Frank DA, Vaidya
VS. A bioinformatics approach identifies signal transducer and activator of
transcription-3 and checkpoint kinase 1 as upstream regulators of kidney injury
molecule-1 after kidney injury. J Am Soc Nephrol. 2014;25(1):105-18.
26. Cao W, Ryan M, Buckley D, O′Connor R, Clarkson MR. Tim-4 inhibition
of T-cell activation and T helper type 17 differentiation requires both the
immunoglobulin V and mucin domains and occurs via the mitogen-activated
protein kinase pathway. Immunology. 2011;133(2):179-89.
27. Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV.
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat
Med. 2010;16(5):535-43, 1p following 143.
28. Forbes JM, Hewitson TD, Becker GJ, Jones CL. Ischemic acute renal
failure: long-term histology of cell and matrix changes in the rat. Kidney Int.
2000;57(6):2375-85.
29. Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney
Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule
injury. Kidney Int. 2002;62(1):237-44.41
30. Bonventre JV. Dedifferentiation and proliferation of surviving epithelial
cells in acute renal failure. J Am Soc Nephrol. 2003;14 Suppl 1:S55-61.
31. Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV. Kidney
injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced
renal injury. Am J Physiol Renal Physiol. 2004;286(3):F552-63.
32. Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV.
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early
detection of kidney tubular injury. Am J Physiol Renal Physiol.
2006;290(2):F517-29.
33. Han WK, Alinani A, Wu CL, Michaelson D, Loda M, McGovern FJ, et
al. Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal
cell carcinoma. J Am Soc Nephrol. 2005;16(4):1126-34.
34. Gautier JC, Zhou X, Yang Y, Gury T, Qu Z, Palazzi X, et al. Evaluation
of novel biomarkers of nephrotoxicity in Cynomolgus monkeys treated with
gentamicin. Toxicol Appl Pharmacol. 2016;303:1-10.
35. Sinha V, Vence LM, Salahudeen AK. Urinary tubular protein-based
biomarkers in the rodent model of cisplatin nephrotoxicity: a comparative
analysis of serum creatinine, renal histology, and urinary KIM-1, NGAL, and
NAG in the initiation, maintenance, and recovery phases of acute kidney injury.
J Investig Med. 2013;61(3):564-8.
36. Zhou Y, Vaidya VS, Brown RP, Zhang J, Rosenzweig BA, Thompson
KL, et al. Comparison of kidney injury molecule-1 and other nephrotoxicity
biomarkers in urine and kidney following acute exposure to gentamicin, mercury,
and chromium. Toxicol Sci. 2008;101(1):159-70.
37. Cuadros T, Trilla E, Vilà MR, de Torres I, Vilardell J, Messaoud NB, et
al. Hepatitis A virus cellular receptor 1/kidney injury molecule-1 is a
susceptibility gene for clear cell renal cell carcinoma and hepatitis A virus
cellular receptor/kidney injury molecule-1 ectodomain shedding a predictive
biomarker of tumour progression. Eur J Cancer. 2013;49(8):2034-47.
38. Lin F, Zhang PL, Yang XJ, Shi J, Blasick T, Han WK, et al. Human
kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for
diagnosing renal cell carcinoma and ovarian clear cell carcinoma. Am J Surg
Pathol. 2007;31(3):371-81.
39. Zheng X, Xu K, Chen L, Zhou Y, Jiang J. Prognostic value of TIM-1
expression in human non-small-cell lung cancer. J Transl Med. 2019;17(1):178.
40. Vilà MR, Kaplan GG, Feigelstock D, Nadal M, Morote J, Porta R, et al.
Hepatitis A virus receptor blocks cell differentiation and is overexpressed in
clear cell renal cell carcinoma. Kidney Int. 2004;65(5):1761-73.
41. Vermeulen R, Zhang L, Spierenburg A, Tang X, Bonventre JV, Reiss B,
et al. Elevated urinary levels of kidney injury molecule-1 among Chinese factory
workers exposed to trichloroethylene. Carcinogenesis. 2012;33(8):1538-41.
42. Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV.
Shedding of kidney injury molecule-1, a putative adhesion protein involved in
renal regeneration. J Biol Chem. 2002;277(42):39739-48.
43. Zhang PL, Mashni JW, Sabbisetti VS, Schworer CM, Wilson GD,
Wolforth SC, et al. Urine kidney injury molecule-1: a potential non-invasive42
biomarker for patients with renal cell carcinoma. Int Urol Nephrol.
2014;46(2):379-88.
44. Ichimura T, Brooks CR, Bonventre JV. Kim-1/Tim-1 and immune cells:
shifting sands. Kidney Int. 2012;81(9):809-11.
45. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM,
et al. KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent
clearance of apoptotic cells to antigen presentation. Embo j. 2015;34(19):2441-
64.
46. Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, et al.
KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest.
2015;125(4):1620-36.
47. de Souza AJ, Oak JS, Jordanhazy R, DeKruyff RH, Fruman DA, Kane
LP. T cell Ig and mucin domain-1-mediated T cell activation requires
recruitment and activation of phosphoinositide 3-kinase. J Immunol.
2008;180(10):6518-26.
48. Cuadros T, Trilla E, Sarró E, Vilà MR, Vilardell J, de Torres I, et al.
HAVCR/KIM-1 activates the IL-6/STAT-3 pathway in clear cell renal cell
carcinoma and determines tumor progression and patient outcome. Cancer Res.
2014;74(5):1416-28.
49. Xu J, Sun L, Sun W, Tian J, Guo H. Targeted Silencing of Kim-1 Inhibits
the Growth of Clear Cell Renal Cell Carcinoma Cell Line 786-0 In Vitro and In
Vivo. Oncol Res. 2018;26(7):997-1003.
50. Thomas LJ, Vitale L, O′Neill T, Dolnick RY, Wallace PK, Minderman H,
et al. Development of a Novel Antibody-Drug Conjugate for the Potential
Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1. Mol
Cancer Ther. 2016;15(12):2946-54.
51. Kondratowicz AS, Lennemann NJ, Sinn PL, Davey RA, Hunt CL,
Moller-Tank S, et al. T-cell immunoglobulin and mucin domain 1 (TIM-1) is a
receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proc Natl Acad
Sci U S A. 2011;108(20):8426-31.
52. Mariat C, Degauque N, Balasubramanian S, Kenny J, DeKruyff RH,
Umetsu DT, et al. Tim-1 signaling substitutes for conventional signal 1 and
requires costimulation to induce T cell proliferation. J Immunol.
2009;182(3):1379-85.
53. Mesri M, Smithson G, Ghatpande A, Chapoval A, Shenoy S, Boldog F,
et al. Inhibition of in vitro and in vivo T cell responses by recombinant human
Tim-1 extracellular domain proteins. Int Immunol. 2006;18(3):473-84.
54. Meyers JH, Chakravarti S, Schlesinger D, Illes Z, Waldner H, Umetsu
SE, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction
regulates T cell proliferation. Nat Immunol. 2005;6(5):455-64.
55. Schweigert O, Dewitz C, Möller-Hackbarth K, Trad A, Garbers C, RoseJohn S, et al. Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4
generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to
phosphatidylserine. Biochim Biophys Acta. 2014;1843(2):275-87.43
56. Sizing ID, Bailly V, McCoon P, Chang W, Rao S, Pablo L, et al. Epitopedependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity
and lung immune responses. J Immunol. 2007;178(4):2249-61.
57. Curtiss M, Colgan J. The role of the T-cell costimulatory molecule Tim-
1 in the immune response. Immunol Res. 2007;39(1-3):52-61.
58. Mijuskovic M, Stanojevic I, Milovic N, Cerovic S, Petrovic D, Maksic D,
et al. Tissue and urinary KIM-1 relate to tumor characteristics in patients with
clear renal cell carcinoma. Int Urol Nephrol. 2018;50(1):63-70.
59. Morrissey JJ, London AN, Lambert MC, Kharasch ED. Sensitivity and
specificity of urinary neutrophil gelatinase-associated lipocalin and kidney
injury molecule-1 for the diagnosis of renal cell carcinoma. Am J Nephrol.
2011;34(5):391-8.
60. Scelo G, Muller DC, Riboli E, Johansson M, Cross AJ, Vineis P, et al.
KIM-1 as a Blood-Based Marker for Early Detection of Kidney Cancer: A
Prospective Nested Case-Control Study. Clin Cancer Res. 2018;24(22):5594-
601.
61. Song J, Yu J, Prayogo GW, Cao W, Wu Y, Jia Z, et al. Understanding
kidney injury molecule 1: a novel immune factor in kidney pathophysiology.
Am J Transl Res. 2019;11(3):1219-29.
62. Cairns P. Renal cell carcinoma. Cancer Biomark. 2010;9(1-6):461-73.
63. Kuo CY, Lin CH, Hsu T. VHL Inactivation in Precancerous Kidney Cells
Induces an Inflammatory Response via ER Stress-Activated IRE1α Signaling.
Cancer Res. 2017;77(13):3406-16.
64. Xue J, Li Y, Yi J, Jiang H. HAVCR1 Affects the MEK/ERK Pathway in
Gastric Adenocarcinomas and Influences Tumor Progression and Patient
Outcome. Gastroenterol Res Pract. 2019;2019:6746970.
65. Mack NA, Whalley HJ, Castillo-Lluva S, Malliri A. The diverse roles of
Rac signaling in tumorigenesis. Cell Cycle. 2011;10(10):1571-81.
66. Drucker BJ. Renal cell carcinoma: current status and future prospects.
Cancer Treat Rev. 2005;31(7):536-45.
67. Ricketts CJ, Morris MR, Gentle D, Brown M, Wake N, Woodward ER,
et al. Genome-wide CpG island methylation analysis implicates novel genes in
the pathogenesis of renal cell carcinoma. Epigenetics. 2012;7(3):278-90.
68. Wu X, Scelo G, Purdue MP, Rothman N, Johansson M, Ye Y, et al. A
genome-wide association study identifies a novel susceptibility locus for renal
cell carcinoma on 12p11.23. Hum Mol Genet. 2012;21(2):456-62.
69. Liu L, Song Z, Zhao Y, Li C, Wei H, Ma J, et al. HAVCR1 expression
might be a novel prognostic factor for gastric cancer. PLoS One.
2018;13(11):e0206423.
70. Kishimoto W, Nishikori M, Arima H, Miyoshi H, Sasaki Y, Kitawaki T,
et al. Expression of Tim-1 in primary CNS lymphoma. Cancer Med.
2016;5(11):3235-45.
71. Wang Y, Martin TA, Jiang WG. HAVcR-1 expression in human
colorectal cancer and its effects on colorectal cancer cells in vitro. Anticancer
Res. 2013;33(1):207-14.44
72. Wang H, Zhang X, Sun W, Hu X, Li X, Fu S, et al. Activation of TIM1
induces colon cancer cell apoptosis via modulating Fas ligand expression.
Biochem Biophys Res Commun. 2016;473(2):377-81.
72. Hagiwara, Yuki (2016) Study of the association between inflammation and the
initiation of renal cell carcinoma: microarray-based gene profiling analysis. Thesis,
National Central University.
73. The microarray data: Deposited in Gene Expression Omnibus (GEO) and are
accessible through GEO Series accession number GSE116326
(https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE116326). |