||1.Allison, D. B., and Fontaine, K. R. (1999). Annual deaths attribuatable to obesity in the Unite States, JAMA 282:1530-1538.|
2.Benito M, Valverde A, and Lorenzo M. (1996) IGF-I: a mitogen also involved in differentiation processes in mammalian cells. Int J Biochem Cell Biol 28:499–510.
3.Boney, C. M., Sekimoto, H., Gruppuso, P. A., and Frackelton, A. R. (2001). Src family tyrosine kinses participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells. Cell Growth & Differentiation 12:379-386.
4.Bray, G. A., and Tartaglia, L. A. (2000). Medicinal strategies in the treatment of obesity, Nature 404: 72-677.
5.Brissenden JE, Ullrich A., and Francke U. (1984) Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor. Nature 310:781-784.
6.Chung, L. Y., Cheung, T. C., Kong, S. K., Fung, K. P., Choy, Y. M., Chan, Z. Y., and Kwok, T. T. (2001). Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells, Life Sci 681:207-14.
7.Daughaday WH, and Rotwein P. (1989) Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 10:68-91.
8.Dulloo, A., G, and Duret, C. (1999). Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h expenditure and fat oxidation in humans, Am J Clin Nutr 70:1040-1045.
9.Kao, Y. H., Hiipakka, R. A., and Liao, S. (2000). Modulation of endocrine systems and food intake by green tea epigallocatechin gallate, Endocrinology 141:980-7.
10.Kavanagh, K. T., Hafer, L. J., Kim, D. W., Mann, K. K., Sherr, D. H., Rogers, A. E., and Sonenshein, G. E. (2001). Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture, J Cell Biochem 82:387-98.
11.Kopelman, P. G. (2000). Obesity as a medical problem, Nature 404:635-643.
12.LeRoith D, Werner H, Beitner-Johnson D and Roberts CT, Jr. (1995) Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev 16:143-163.
13.Liang, Y. C., Lin-shiau, S. Y., Chen, C. F., and Lin, J. K., (1997). Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-Epigallocatechin allate in human A431 epidermoid carcinoma cells. J Cell Biochem 65:55-65.
14.Liang, Y. C., Lin Shiau, S. Y., Chen, C. F., and Lin, J. K. (1999). Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate, J Cell Biochem 75:1-12.
15.Liberto, M., and Cobrinik, D. (2000). Growth factor-dependent induction of p21(CIP1) by the green tea polyphenol, epigallocatechin gallate, Cancer Lett 154:151-61.
16.Morrison, R. F., and Farmer, S. R. (1999). Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis, J Biol Chem 274:17088-97.
17.Must, A., Field, A. E., and Dietz, W. H. (1999). The disease burden association with overweight and obesity, JAMA 282:1523-1529.
18.Opare Kennedy, D., Kojima, A., Hasuma, T., Yano, Y., Otani, S., and Matsui Yuasa, I. (2001). Growth inhibitory effect of green tea extract and (-)-epigallocatechin in Ehrlich ascites tumor cells involves a cellular thiol-dependent activation of mitogenic-activated protein kinases, Chem Biol Interact 134:113-33.
19.Paschka, A. G., Butler, R., and Young, C. Y. (1998). Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate, Cancer Lett 130:1-7.
20.Phelps, D. E., and Xiong, Y. (1998). Regulation of cyclin-dependent kinase 4 during adipogenesis involves switching of cyclin D subunits and concurrent binding of p18INK4c and p27Kip1, Cell Growth Differ 9:595-610.
21.Rosenfeld RG and Roberts CTJ. The IGF System; Molecular Biology, Physiology, and Clinical Applications. Humana Press Inc., Totowa, New Jersey, 1999.
22.Saeki, K., Hayakawa, S., Isemura, M., and Miyase, T. (2000). Importance of a pyrogallol-type structure in catechin compounds for apoptosis-inducing activity, Phytochemistry 53:391-4.
23.Stewart C., and Rotwein P. (1999). Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol. Rev., 76:1005-1026.
24.Tai, T. Y., Chuang, L. M., and Wu, H. P. (1992). Association of body bulid with non-insulin-dependent diabets mellitus and hypertension among Chinese adults, Int J Epidemiol 21:511-517.
25.Tan, X., Hu, D., Li, S., Han, Y., Zhang, Y., and Zhou, D. (2000). Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells, Cancer Lett 158:1-6.
26.Ullrich A, Gray A, Tam AW, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, and Chen E (1986). Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. Embo J 5:2503-2512.
27.Ullrich A and Schlessinger J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
28.Watanabe, J., and Niki, R. (1998). isolation and identification of acetyl-coA carboxylase inhibitors from green tea, Biosci Biophys Biochem 62:532-534.