博碩士論文 93327006 詳細資訊




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姓名 洪群泰(Cyun-Tai Hong)  查詢紙本館藏   畢業系所 光機電工程研究所
論文名稱 全場相位式表面電漿共振技術
(Surface plasmon resonance technique with full-field phase detection)
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摘要(中) 本研究以偏振干涉術配合SPR技術,再結合了CCD取像,整合出可以量測出一整面的折射率分佈的全場SPR相位儀。本解相系統的相位解析度為0.3度,整體系統對折射率的靈敏度為3*10^-6 RIU(Refractive Index Unit, RIU)。本論文之實驗為量測出細微折射率的改變,以及驗證系統基本功能。此相位儀在實驗上可以分辨出濃度差1%酒精溶液(折射率差約0.0004RIU)。本系統具有即時、高靈敏度、大量平行篩檢等優點。若能實際結合生醫微陣列晶片的設計,對於量測生物分子的反應、DNA檢測等,均有廣泛的應用。
摘要(英) A surface plasmon resonance (SPR) technique with full-field phase detection is proposed. In our full field system, we combine a method of the polarization interference for phase detection, SPR technique and CCD Video camera. The resolution of phase detection is about 0.3 degree, and the measurement sensitivity of refractive index is about 3*10^-6 RIU (Refractive Index Unit). There are several advantages like immediate detection, high sensitivity and parallel examining in our system .
關鍵字(中) ★ 全場量測
★ 表面電漿共振
★ 偏振干涉術
關鍵字(英) ★ SPR
★ polarization interference
★ full-field detection
論文目次 第一章 緒論………………………………….………………..1
1-1 前言……………………………………………………...……….1
1-2 文獻回顧…………………………………………………...…….2
1-3 實驗動機與目的………………………………………...……….6
1-4 論文架構.………………………………………...………...…….7
第二章 SPR基本原理………………………..………………..9
2-1 SPR原理…………………………...…………………………….9
2-2 激發表面電漿波的方式 ………………………………………..13
2-3 kretschmann組態……………………………….………………..17
2-4 小結……………………………………………………….……..21
第三章 解相位理論…………………………...………………22
3-1 解相位架構………………….…………………………………..22
3-2 JONES CALCULATION…………………….………………….24
3-3 全場折射率分佈模擬……………………….…………………..26
3-4 利用四方之一波片當待測物驗證結果與討論…………..…….29
3-5 小結……………………………………………………………..31
第四章 系統設計與架構……………….…...………………..32
4-1 SPR感測器設計.………………………………………………..32
4-2 機構設計…………………….………………………………….35
4-3 整體實驗儀器與架構…………………….…………………….39
4-4 控制程式介面與流程………………………….……………….43
4-5 小結…………………………….……………………………….46
第五章 實驗結果與討論………….…………………………..47
5-1 實驗準備……………………………….……………………….47
5-2 實驗一…………………………………………….…………….51
5-3 實驗二……………………………………………….………….63
5-4 誤差來源分析…………………………………………….…….66
5-5 系統靈敏度分析………………………………………….…….68
5-6 實驗結果…………………………………………….………….72
第六章 結論…………………………………………………..73
參考文獻………………………………………………………74
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指導教授 李朱育(Ju-Yi Lee) 審核日期 2006-7-19
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