博碩士論文 953207003 詳細資訊




以作者查詢圖書館館藏 以作者查詢臺灣博碩士 以作者查詢全國書目 勘誤回報 、線上人數:13 、訪客IP:35.172.195.49
姓名 劉冠彣(Gwan-Wun Liu)  查詢紙本館藏   畢業系所 光機電工程研究所
論文名稱 光強差動式表面電漿共振感測術之研究
(Differential surface plasmon resonance sensing technique)
相關論文
★ MOCVD晶圓表面溫度即時量測系統之開發★ MOCVD晶圓關鍵參數即時量測系統開發
★ 全場相位式表面電漿共振技術★ 波長調制外差式光柵干涉儀之研究
★ 攝像模組之影像品質評價系統★ 雷射修整之高速檢測-於修整TFT-LCD SHORTING BAR電路上之應用
★ 準共光程外差光柵干涉術之研究★ 波長調制外差散斑干涉術之研究
★ 全場相位式表面電漿共振生醫感測器★ 利用Pigtailed Laser Diode 光學讀寫頭在角度與位移量測之研究
★ 複合式長行程精密定位平台之研究★ 紅外波段分光之全像集光器應用
★ 太陽光譜分光器之設計★ 波長調制旋光外差干涉術應用於表面電漿共振偵測
★ 疊紋自動對焦技術★ 以Fabry Perot Etalon 做雷射高斯光束發散角量測之研究
檔案 [Endnote RIS 格式]    [Bibtex 格式]    [相關文章]   [文章引用]   [完整記錄]   [館藏目錄]   [檢視]  [下載]
  1. 本電子論文使用權限為同意立即開放。
  2. 已達開放權限電子全文僅授權使用者為學術研究之目的,進行個人非營利性質之檢索、閱讀、列印。
  3. 請遵守中華民國著作權法之相關規定,切勿任意重製、散佈、改作、轉貼、播送,以免觸法。

摘要(中) 本研究以差動偵測技術結合表面電漿共振技術,開發出一種光強差動式的表面電漿共振(Surface Plasmon Resonance,SPR)偵測技術。本系統由實驗所得的對折射率解析度約為 10-5 RIU。本論文的實驗目的為偵測微小的折射率變化,以及驗證出系統的功能。在實驗上,可分辨出折射率相差0.0001 RIU折射率的不同濃度酒精溶液。本系統具有即時偵測、高靈敏度等優點,預計可應用於微小生物分子鍵結反應的檢測領域上。未來若能應用於生物分子陣列晶片上,將能達到大量平行篩檢的應用上,以求本系統對生醫檢測有所貢獻。
摘要(英) An optical differential detection technique for the surface plasmon resonance (SPR) sensing is proposed. In our system, we combine a method of differential detection and SPR technique. The measurement sensitivity of refractive index is about 10-5 RIU (Refractive Index Unit). There are several advantages like immediate detection and high sensitivity in our system. This technique can be applied to the small biological molecule interaction. It is expected to combine the biological molecule on bio-chip array for massive parallel screens.
關鍵字(中) ★ 差動偵測
★ 表面電漿共振
關鍵字(英) ★ differential detection
★ Surface plasmon resonance
論文目次 摘要 I
Abstract II
目錄 IV
圖 目 錄 VI
表 目 錄 IX
符 號 說 明 X
第一章 緒論 - 1 -
1-1 前言 - 1 -
1-2 文獻回顧 - 3 -
1-3 研究動機與目的 - 7 -
1-4 論文架構 - 8 -
第二章 差動表面電漿共振原理 - 10 -
2-1 表面電漿共振原理 - 10 -
2-2 激發表面電漿波的方式 - 11 -
2-3表面電漿共振反射光強度與入射角的關係 - 14 -
2-4 反射光強度差動偵測原理 - 17 -
2-5 小結 - 23 -
第三章 系統設計與架構 - 24 -
3-1 感測片參數設計 - 24 -
3-2 機構設計 - 28 -
3-3 整體架構 - 31 -
3-4 程式設計 - 35 -
3-5 小結 - 40 -
第四章 實驗結果與討論 - 41 -
4-1 實驗準備 - 41 -
4-2 實驗一:小範圍酒精濃度測試 - 48 -
4-3 實驗二:大範圍酒精濃度測試 - 51 -
4-4 誤差來源與分析 - 54 -
4-5 系統解析度分析 - 61 -
4-6 小結 - 63 -
第五章 結論 - 64 -
參考文獻 - 65 -
參考文獻 [01]. 安毓英、曾小東,光學感測與量測,五南圖書,台北市,2004 年。
[02]. 林宸生、陳德請,近代光電工程導論,全華圖書,台北市,民國93 年3 月。
[03]. K. Matsubara, S. Kawata, and S. Minami, “Optical chemical sensor based on surface plasmon measurement”, APPLIED OPTICS, Vol. 27, No. 6,P 1160-1163, 1988.
[04]. A. V. Kabashin and P. I. Nikitin, “Surface plasmon resonance interferometer for bio-and chemical-sensors”, Optics Communications, Vol. 150, No. 1, pp. 5-8, 1998.
[05]. D. K. Kambhampati and W. Knoll, “Surface-plasmon optical techniques” , Current Opinion in Colloid & Interface Science, Vol. 4, No. 5, pp. 273-280, 1999.
[06]. R. J. Green, R. A. Frazier, K. M. Shakesheff, M. C. Davies, C. J. Roberts, and S. J. B. Tendler, “Surface plasmon resonance analysis of dynamic biological interactions with biomaterials” , Biomaterials, Vol. 21, No. 18, pp. 1823-1835, 2000.
[07]. Y. D. Su, S. J. Chen, and T. L. Yeh, “Common-path phase-shit interferometry surface plasmon resonance imaging system” , Optics Letters, Vol. 30, No. 12, pp. 1488-1490, 2005.
[08]. K. Johansen, H. Arwin, I. Lundstrom, and B. Liedberga, “Imaging surface plasmon resonance sensor based on multiple sensitivity considerations”, Review of Scientific Instruments, Vol. 71, No. 9, pp. 3530-3538, 2000.
[09]. H. E. De Bruijin, B. S. F. Altenburg, R. P. H. Kooyman, and J.Greve, “Determination of thickness and dielectric constant of thin transparent dielectric layers using surface plasmon resonance”, Optics Communications, Vol. 82, pp. 425-432, 1991.
[10]. M. T. Flanagan and R. H. Pantell, “Surface plasmon resonance and immunosensors”, Electronics Letters, Vol. 20, pp. 968-970, 1984.
[11]. J. W. Sadowski, J. Lekkala, and I. Vikholm, “Biosensors based on surface plasmons excited in non-noble metals”, Biosensors & Bioelectronics, Vol. 6, pp. 439-444, 1991.
[12]. K. Matsubara, S. Kawata, and S. Minami, “A compact surface Plasmon resonance sensor for measurement of water in process”, Applied Spectroscopy, Vol. 42, pp. 1375-1379 , 1988.
[13]. R. C. Jorgenson and S. S. Yee, “A fiber-optic chemical sensor based on surface plasmon resonance”, Sensors and Actuators B: Chemical, Vol. 12, pp. 213–220, 1993.
[14]. X. Sun, S. Shiokawa, and Y. Matsui, “Interaction of surface plasmons with surface acoustic waves and the study of the properties of Ag films”, Journal of Applied Physics, Vol. 69, pp. 362–366, 1991.
[15]. P. D. Gershon and S. Khilko, “Stable chelating linkage for reversible immobilization of oligohistidine tagged proteins in the BIAcore Surface Plasmon Resonance detector”, Journal of Immunological Methods, Vol. 183, pp. 65–76, 1995 .
[16]. R. McKendry, J. Zhang, Y. Arntz, T. Strunz, M. Hegner, H.P. Lang, M.K. Baller, U. Certa, E. Meyer, H. Guntherodt and C. Gerber, “ Multiple label-free biodetection and quantitative DNA-binding assays on a nanomechanical cantilever array”, Proceedings of the National Academy of Science, Vol. 99 , pp. 9783-9788, 2002.
[17]. S. Y. Wu, H. P. Ho, W. C. Law, and Chinlon Lin, “ Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach-Zender configuration”, Optics Letters, Vol. 29, pp. 2378-2380, 2004.
[18]. R. H. Ritchie, “ Plasma Losses by fast electrons in thin films”, Physical Review, Vol. 106, pp. 874-881, 1957.
[19]. C. J. Powell and J. B. Swan, “ Origin of the Characteristic Electron Energy Losses in Magnesium”, Physical Review, Vol. 116, pp. 81-83, 1959.
[20]. B. Liedberg, C. Nylander, I. Lundstroem, “Surface plasmon resonance for gas detection and biosensing”, Sensors and Actuator, Vol. 4, pp. 299-304, 1983.
[21]. S. F. Wang, M. H. Chiu, C. W. Lai and R. S. Chang, ” High-sensitivity small-angle sensor based on surface plasmo resonance technology and heterodyne interferometry”, Applied Optics, Vol. 45, pp. 6702-6707, 2006.
[22]. S. Shen, T. Liu and J. Guo, “ Optical phase-shift detection of surface plasmon resonance”, Applied Optics, Vol. 37, pp. 1747-1751, 1998.
[23]. R. Georgiadis and K. A. Peterlinz , “Surface plasmon resonance spectroscopy as a probe of in-plane polymerization in monolayer organic conducting films”, American Chemical Society, Vol. 16, No. 17, pp. 6759-6763, 2000.
[24]. A.A. Kolomenskii and P. D. Gershon, “Sensitivity and detection limit of concentration and adsorption measurements by laser-induced surface-plasmon resonance”, Applied Optics, Vol. 36, No. 25, pp. 6539-6548, 1997.
[25]. H. E. Brujin, R. P. H. Kooyman, and J. Greve, “Choice of metal and wavelength for surface plasmon resonance sensors: some considerations”, Applied Optics, Vol. 31, pp. 440–442, 1992.
[26]. S. Otsuki, K. Murai, and S. Yoshikawa, “Development of a two-dimensional evaluation method for thin layers using surface plasmon resonance”, Chemical Letters, Vol. 30, pp. 1312–1313, 2001.
[27]. S. Otsuki, K. Tamada, and S. Wakida, “Wavelength-scanning surface plasmon resonance imaging”, Applied Optics, Vol. 44, No. 17, pp. 3468-3472, 2005.
[28]. I. Stemmler, A. Brecht, and G. Gauglitz, “Compact surface plasmon resonance-transducers with spectral readout for biosensing applications”, Sensors and Actuators B: Chemical, Vol. 54, pp. 98-105, 1999.
[29]. E. Stenberg, B. Persson, H. Roos, and C. Urbaniczky, “Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins”, Journal of colloid and interface science, Vol. 143, pp. 513-526, 1991 .
[30]. B. Chadwick and M. Gal, “An optical temperature sensor using surface plasmons”, Japanese Journal of Aapplied Physics, Vol. 32, pp. 2716-2717, 1993.
[31]. S. G. Nelson, K. S. Johnston and S. S. Yee, “High sensitivity surface plasmon resonance sensor based on phase detection”, Sensors and Actuators B: Chemical, Vol. 35, pp. 187-191, 1996.
[32]. H. Suzuki, M. Sugimoto, Y. Matsui and J. Kondoh, “Fundamental characteristics of a dual-colour fibre optic SPR sensor”, Measurement Science and Technology, Vol. 17, pp. 1547-1552, 2006.
[33]. A. Suzuki, J. Kondoh, Y. Matsui, S. Shiokawa and K. Suzuki, “Development of novel optical waveguide surface plasmon resonance (SPR) sensor with dual light emitting diodes”, Sensors and Actuators B: Chemical, Vol. 106 , pp. 383-387, 2005.
[34]. A. Hemmi, T. Imato , Y. Aoki , M. Sato , N.i Soh, Y. Asano, C. Akasaka, S. Okutani, S. Ohkubo, N. Kaneki, K. Shimada, T. Eguchi and T. Oinumae , “Development of palm-sized differential plasmon resonance meter based on concept of Sprode”, Sensors and Actuators B: Chemical, Vol. 108, pp. 893-898, 2005.
[35]. E. Stenberg, B. Persson, H. Roos and C. Urbaniczky, “Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins”, Journal of Colloid and Interface Science, Vol. 143, pp. 513–526 , 1991.
[36]. J. H. Chen and Y. C. Chang, “ Measuring small wavelength differences by heterodyne interferometry and optical activity of chiral crystal”, Optics Communications, Vol. 267, pp. 82-186, 2006.
[37]. 吳民耀、劉威志,表面電漿子理論與模擬,物理雙月刊(廿八卷二期)2006 年4 月。
[38]. N. Destouches, H. Giovannini, and M. Lequime, “Interferometric measurement of the phase of diffracted waves near the plasmon resonances of metallic gratings”, Applied Optics, Vol. 40, No. 31, pp. 5575-5583, 2001.
[39]. S. Patskovsky, A. V. Kabashin, M. Meunier, and J. H. T. Luong, “Silicon-based surface plasmon resonance sensing with two surface plasmon polariton modes”, Applied Optics, Vol. 42, No. 34, pp. 6905-6910, 2003.
[40]. A. Otto, “Excitation of nonradiative surface plasma waves in silver by the method of frustrated total reflection”, Zeitschrift Fur Physik a Hadrons and Nuclei, Vol. 216, No. 4, pp. 398-410, 1968.
[41]. J. Homola, S. S. Yee, and G. Gauglitz, “Surface plasmon resonance sensors: review”, Sensors and Actuators B: Chemical, Vol. 54, No. 1, pp. 3-15, 1999.
[42]. J. Homola, I. Koudela, and S. S. Yee, “Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison”, Sensors and Actuators B: Chemical, Vol. 54, No. 1, pp. 16-24, 1999.
[43]. A. Arce, A. Arce Jr. and A. Soto, “Physical and excess properties of binary and ternary mixtures of 1,1-dimethylethoxy-butane, methanol, ethanol and water at 298.15K”, Fluid Phase Equilibria , Vol. 435 , pp. 197-201, 2005.
[44]. 周登科,全場相位式表面電漿共振生醫感測器,中央大學,2007年七月。
[45]. P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density”, Journal of Physical and Chemical Reference Data, Vol. 19, No. 3, pp. 677-717, 1990.
[46]. 吳維庭,準共光程外差光柵干涉術之研究,中央大學,2008年七月。
指導教授 李朱育(Ju-yi Lee) 審核日期 2008-7-17
推文 facebook   plurk   twitter   funp   google   live   udn   HD   myshare   reddit   netvibes   friend   youpush   delicious   baidu   
網路書籤 Google bookmarks   del.icio.us   hemidemi   myshare   

若有論文相關問題,請聯絡國立中央大學圖書館推廣服務組 TEL:(03)422-7151轉57407,或E-mail聯絡  - 隱私權政策聲明