連續血壓量測系統的改良與驗證

以作者查詢圖書館館藏

、以作者查詢臺灣博碩士

、以作者查詢全國書目

、勘誤回報

、線上人數：54

、訪客IP：18.218.207.253

姓名

徐大川(Ta-chuan Hsu) 查詢紙本館藏

畢業系所

電機工程學系

論文名稱

連續血壓量測系統的改良與驗證
(Improvement and Verification of Continuous Blood Pressure Measurement Systems)

相關論文

★ 影像處理運用於家庭防盜保全之研究	★ 適用區域範圍之指紋辨識系統設計與實現
★ 頭部姿勢辨識應用於游標與機器人之控制	★ 應用快速擴展隨機樹和人工魚群演算法及危險度於路徑規劃
★ 智慧型機器人定位與控制之研究	★ 基於人工蜂群演算法之物件追蹤研究
★ 即時人臉偵測、姿態辨識與追蹤系統實現於複雜環境	★ 基於環型對稱賈柏濾波器及SVM之人臉識別系統
★ 改良凝聚式階層演算法及改良色彩空間影像技術於無線監控自走車之路徑追蹤	★ 模糊類神經網路於六足機器人沿牆控制與步態動作及姿態平衡之應用
★ 四軸飛行器之偵測應用及其無線充電系統之探討	★ 結合白區塊視網膜皮層理論與改良暗通道先驗之單張影像除霧
★ 基於深度神經網路的手勢辨識研究	★ 人體姿勢矯正項鍊配載影像辨識自動校準及手機接收警告系統
★ 模糊控制與灰色預測應用於隧道型機械手臂之分析	★ 模糊滑動模態控制器之設計及應用於非線性系統

檔案

[Endnote RIS 格式]

[Bibtex 格式]

[相關文章]

[文章引用]

[完整記錄]

[館藏目錄]

[檢視]

[下載]

本電子論文使用權限為同意立即開放。
已達開放權限電子全文僅授權使用者為學術研究之目的，進行個人非營利性質之檢索、閱讀、列印。
請遵守中華民國著作權法之相關規定，切勿任意重製、散佈、改作、轉貼、播送，以免觸法。

摘要(中)

本研究旨在藉由低度壓力的量測方式實現連續血壓系統，並且針對先前之系統進行硬體的改良以及軟體功能建構，本文亦提出改進連續血壓轉換公式以達到較穩定的血壓動態變化。
測量連續血壓變化的時候，在上臂或手腕包覆壓脈袋，並將空氣灌進壓脈袋，以低度壓力(30~60mmHg)壓迫上臂的血管，受壓迫的血管中血流壓力回傳至壓脈袋與壓力感測器，壓力感測器的輸出信號傳送到兩個類比輸入通道，再透過個人電腦進行血壓參數的計算，並且即時顯示經低壓轉換所得之血壓值及心跳頻率。本系統的人機介面是由虛擬儀控程式LabVIEW所設計，並經由NI-DAQ USB-6009資料擷取卡，做數位輸出以及類比輸入的工作。
為確認本系統的準確性，本研究分別採用血壓計與心率變異儀的量測數值與連續血壓量測的結果比較。經過實際測試的數據分析，本系統所使用低度壓力量測方式與市面上的血壓計結果吻合。此外，本文利用梅爾波（Mayer waves）來觀察長時間血壓變化，而連續血壓系統量測到的低頻血壓頻譜與心率變異儀所量測的低頻的血壓變異一致，因此本研究驗證了連續血壓方法的準確性與穩定性。
本研究改進低壓連續量測系統的血壓動態追蹤功能，並且提高了系統的穩定性與精準度，實驗結果證實低壓量測方法符合非侵入式自動血壓計型式認證技術規範。

摘要(英)

The main purpose of the research is to design a continuous blood pressure (BP) measurement system based on low pressure approach. In this study, we modify the low pressure translating formula of continuous blood pressure and improve the hardware of system to achieve the more accurate tracking capability of dynamic blood pressure.
The measurement of continuous blood pressure is achieved by applying cuff on the arm or wrist of subjects. The cuff is filled with air and maintained in low pressure (30~60mmHg). The signals of cuff pressure and pulse vibration are at the output of the pressure sensor. A filtering and amplifying circuit is introduced to separate the two signals into two analog input channels of Data Acquisition Card. Thus, blood pressure and heart rate can be calculated after acquiring the data by the personal computer. The interface of the system is completed by LabVIEW. The digital output and the analog input signals are operated by utilizing National Instruments Data Acquisition Multifunction I/O Card.
Moreover, Mayer waves at subjects’ wrist artery for evaluating the blood pressure variation (BPV) in low frequency is recorded. The estimated BPV is verified with the commercial heart rate variation (HRV) equipment. According to the experimental results, it proves that the accuracy and stability of the continuous blood pressure measurement systems.
In this thesis, a modified dynamic blood pressure (BP) measurement system is proposed. By the experimental results, it is shown that the accuracy and the stability of proposed system could meet the requirement of Non-Invasive Automated Sphygmomanometers standard (AAMI SP10).

關鍵字(中)

★ 心率變異
★ 血壓
★ 低壓量測

關鍵字(英)

★ low cuff pressure approach
★ blood pressure
★ heart rate variation

論文目次

中文摘要
Abstract
誌謝
目錄......................................................i
圖目錄......................................................iv
表目錄......................................................viii
第一章緒論......................................................1
1.1 引言......................................................1
1.2 文獻回顧......................................................2
1.2.1 壓張法(Tonometric method)......................................................3
1.2.2 血管無負載法(Vascular Unloading Method)......................................................4
1.2.3 脈波傳遞時間(Pulse Transit Time)......................................................6
1.2.4 脈波傳遞時間與振盪法間歇性校正......................................................8
1.2.5 恆壓低壓法......................................................9
1.3 研究動機與目的......................................................10
1.4 論文架構......................................................11
第二章研究方法......................................................12
2.1 非侵入式血壓量測......................................................12
2.1.1 聽診法(Auscultation Method)......................................................12
2.1.2 振盪法(Oscillometric Method)......................................................15
2.2 非侵入式連續血壓量測......................................................16
2.2.1 恆壓低壓法......................................................16
2.2.2 連續血壓量測方法的改良......................................................17
第三章連續血壓量測系統......................................................19
3.1 NI USB-6009資料擷取卡......................................................20
3.2 壓力感測器......................................................21
3.3 加壓幫浦及洩壓閥控制......................................................23
3.4 恆壓控制架構......................................................24
3.5 濾波放大電路......................................................26
3.6 人機介面......................................................29
3.6.1 介面軟體介紹......................................................29
3.6.2 圖控式介面設計......................................................30
3.7 連續血壓量測方法......................................................32
3.7.1 第一模式(Mode 1)量測流程......................................................33
3.7.2 心率計算及心跳顯示......................................................35
3.7.3 第二模式(Mode 2)量測流程......................................................36
第四章系統測試與結果討論......................................................38
4.1 硬體測試結果......................................................40
4.1.1 壓脈袋恆壓性能......................................................41
4.2 系統實際測試結果......................................................45
4.2.1 第一模式振盪法量測......................................................45
4.2.2 第二模式低壓量測......................................................47
4.3 血壓動態分析......................................................52
4.3.1 伐耳沙爾瓦氏技巧(Valsalva maneuver)......................................................52
4.3.2 梅爾波(Mayer waves)......................................................59
第五章結論與建議......................................................67
5.1 結論......................................................67
5.2 建議......................................................68
參考文獻......................................................70
附錄A......................................................73
附錄B......................................................74
附錄C......................................................75
List of Publication......................................................76

參考文獻

[1]郭建志,“以恆壓低壓量測連續脈壓訊號”,中原大學電機工程學系碩士論文, 2002.
[2]消基會抽測，電子血壓計3成沒個準
http://www.libertytimes.com.tw/2007/new/nov/13/today-life4.htm
[3]J.J. Carr and J.M. Brown, Introduction to Biomedical Equipment Technology, Prentice hall, fourth edition, 2001.
[4]G.L. Pressman and P.M. Newgard, “A transducer for the continuous external measurement of arterial blood pressure”, IEEE Trans Bio-Med Electron10 , pp. 73-81, 1963.
[5]H. Sorvoja and R. Myllylä,“Noninvasive blood pressure measurement methods”, Molecular and Quantum Acoustics, vol. 27, pp. 239-264, 2006.
[6]K. I. Yamakoshi, H. Shimazu, and T. Togawa, “Indirect measurement of instantaneous arterial blood pressure in the human finger by the vascular unloading technique,” IEEE Trans. Biomed. Eng. , vol. BME-27, No. 3, pp. 150-155, 1980.
[7]P. Fung, G. Dumont, C. Ries, C. Mott and M. Ansermino, “Continuous noninvasive blood pressure measurement by pulse transit time”, in Ann. Int. Conf. IEEE Eng. Med. Biol. Soc., vol.1, pp. 738-741, 2004.
[8]楊坤岳, “以脈波抵達時間與間歇性校正推估連續血壓於姿勢性暈眩之研究”, 中原大學醫學工程學系碩士論文, 2006.
[9]陸坤池,“以低壓實現之非侵入式連續血壓量測系統”, 中原大學醫學工程學系碩士論文, 2000.
[10]范振臺, “可攜式低壓腕部脈搏訊號之量測”, 中原大學電機工程學系碩士論文, 2001.
[11]丁蒼毅,“使用低壓量測方法之連續血壓量測系統”,中央大學電機工程學系碩士論文, 2007.
[12]J. G. Webster, Medical Instrumentation – Application and Design, 3rd edition, John Wiley & Sons, Inc., pp.317-328, 1998.
[13]L. A. Geddes, The Direct and Indirect Measurement of Blood Pressure, Year Book Medical Publishers, 1970.
[14]http://www.medphys.ucl.ac.uk/teaching/undergrad/projects/2003/group_03/how.html
[15]L. A. Geddes, Handbook of Blood Pressure Measurement, Year Book Medical Publishers, 1970.
[16]J.C. T. B. Moraes, M. Cerulli and P.S. Nq, “A strategy for determination of systolic, mean and diastolic blood pressures from oscillometric pulse profiles”, Computers in Cardiology 2002, pp. 211-214, 2000.
[17]National Instruments, “USB-6008/6009 User Guide and Specifications”, 2005.
[18]Freescale Semiconductor, “Integrated Silicon Pressure Sensor On-Chip Signal Conditioned, Temperature Compensated and Calibrated”, 2007.
[19]Freescale Semiconductor, “Digital Blood Pressure Meter”, 2005.
[20]蕭子健, 王智昱, 儲昭偉, 虛擬儀控程式設計LabVIEW 7X, 高立圖書有限公司, 2004.
[21]Association for the Advancement of Medical Instrumentation. “American National Standard for Manual, Electronic, or Automated Sphygmomanometers”, SP10-2002, AAMI, 2003.
[22]J.M. Stewart, M.A. Medow, B. Bassett and L.D. Montgomery, “Effects of thoracic blood volume on Valsalva maneuver”, Am J Physiol Heart Cirs Physiol 287, pp. H798-H804, 2004.
[23]J. Andrew Taylor：HRV and measurement of the arterial baroreflex
www.physionet.org/events/hrv-2006/taylor.pdf
[24]黃峻峰：如廁中風？少量多次用力輕鬆解放
http://cmin.cch.org.tw/health_02.aspx?id=363
[25]徐瑋瑩, “易筋經運動對中年人心率變異的影響”, 南華大學自然醫學研究所碩士論文, 2006.
[26]S. Mayer, “Zur physiologie des gefabnervenzentrums. ”, European Journal of Physiology, vol. 9, pp. 499-513, 1874.
[27]B.M. Sayers, “Analysis of heart rate variability”, Ergonomics 16: 17-32, 1973.
[28]S.R. Seydnejad and R.I. Kitney, “Modeling of Mayer waves generation mechanisms”, IEEE Eng Med Biol Mag, vol. 20, pp. 92-100, 2001.

指導教授

鍾鴻源(Hung-Yuan Chung)

審核日期

2008-7-14

推文