博碩士論文 982202032 詳細資訊




以作者查詢圖書館館藏 以作者查詢臺灣博碩士 以作者查詢全國書目 勘誤回報 、線上人數:46 、訪客IP:3.234.214.179
姓名 吳宗訓(Zong-Syun Wu)  查詢紙本館藏   畢業系所 物理學系
論文名稱 質子照影成像使用GEANT4蒙特卡羅模擬研究
(Study of Proton Range Radiography Imaging Using Geant4 Monte Carlo Simulation)
相關論文
★ 宇宙射線中的質子能譜★ 建構空氣簇射探測器及測量海平面宇宙射線通量
★ 宇宙射線中正電子和電子的能譜★ 宇宙射線中的氦原子核能譜
★ 建構粒子能譜探測器及量測海平面上質子能譜分布★ 偵測大氣內水平行進之緲子用的帶電粒子偵測器陣列之可行性研究
★ 在康卜吞成像光譜儀內的gamma射線事件的分析★ Study of Zγ-> e+e-γ Process with CMS Detector at Large Hadron Collider
★ 利用CMS探測器量測7TeV下的Zγ產生截面★ 康卜吞成像光譜儀數據讀出系統
★ LHC phenomenology and renormalization of Georgi-Machacek model
檔案 [Endnote RIS 格式]    [Bibtex 格式]    [相關文章]   [文章引用]   [完整記錄]   [館藏目錄]   [檢視]  [下載]
  1. 本電子論文使用權限為同意立即開放。
  2. 已達開放權限電子全文僅授權使用者為學術研究之目的,進行個人非營利性質之檢索、閱讀、列印。
  3. 請遵守中華民國著作權法之相關規定,切勿任意重製、散佈、改作、轉貼、播送,以免觸法。

摘要(中) 質子照影(Proton Range Radiography 以下簡稱PRR)在質子治療中是一個影像品質控制工具。病人開始質子治療之前,PRR的即時影像可以使用與質子治療相同的質子束產生。比較PRR的影像與電腦斷層的影像,醫生可以知道腫瘤的變化來評估治療是否有效。PRR是由兩片氣體電子倍增器(Gas Electron Multiplier)以及三十片塑膠閃爍體(Plastic Scintillator)所組成。氣體電子倍增器為記錄粒子軌跡而塑膠閃爍體則是紀錄粒子在閃爍體的能量損失或是粒子距離。本論文主要利用上述兩個條件來重建影像,由這些影像來分析PRR的影像解析度以及找尋最低劑量並保有清晰影像的劑量值。
摘要(英) Proton Range Radiography (PRR) is an image quality control tool in proton therapy. Before a patient begins proton irradiation, a real-time imaging can be generated by the same proton beam. By comparing with the computer tomography image; the doctor can know any changes of tumor to evaluate the validity of the treatment. The PRR detector includes a pair of gas electron multiplier and a range telescope made with a stack of 30 scintillators. The gas electron multiplier is to record the trajectory of the particle and the scintillator is to record the energy loss of particle passing through scintillator. In this thesis, we used these two conditions to reconstruct the image and analysis image resolution from these images. In order to find the minimum dosage require for clean picture, we through a simple algorithm to search the minimum dosage.
關鍵字(中) ★ geant4
★ 質子照影
★ 影像解析度
關鍵字(英) ★ image resolution
★ proton range radiography
★ geant4
論文目次 中文摘要…………………………………………………………………i
Abstract…………………………………………………………………ii
誌謝……………………………………………………………………iii
Contents…………………………………………………………………iv
Figures…………………………………………………………………vii
Tables……………………………………………………………………ix
Chapter 1 Introduction………………………………………………1
1-1 Overview of Proton Therapy ……………………………………1
1-2 Introduction to Proton Range Radiography (PRR)…………1
1-3 Motivation of this Studying……………………………………2
Chapter 2 The Physics of Charged Particle Interaction in Matter……3
2-1 Type Interactions of Charged Particle with Matter ……3
2-1-1 Coulomb Force Interaction of the Charged Particle with Orbital Electron for b >> a (soft collision)……………4
2-1-2 Coulomb Force Interaction of the Charged Particle with Orbital Electron for b ≈ a (hard collision)……………4
2-1-3 Coulomb Force Interaction of the Charged Particle with the External Nuclear Field for b < 2-2 Energy Loss of Charged Particle………………………………6
2-2-1 General Concept of Stopping Power…………………………6
2-2-1-A Bethe Collision Stopping Power for Heavy Charged Particle…………………………………………………………………6
2-2-1-B Mass Radiative Stopping Power……………………………8
2-2-1-C Total Mass Stopping Power of Charged Particle………9
2-2-2 The CSDA Range of Charged Particle………………………9
2-2 Multiple Coulomb Scattering…………………………………11
2-3 The Bragg Peak……………………………………………………12
Chapter 3 Overview of Proton Range Radiography………………14
3-1The Instrument of Proton Range Radiography………………14
3-1-1 Phantom…………………………………………………………15
3-1-2 GEM (Gas Electron Multiplier)……………………………15
3-1-3 Plastic Scintillator…………………………………………17
3-1-4 Wavelength Shifter (WLS)……………………………………18
3-2 Readout System……………………………………………………19
3-3 Beam Test…………………………………………………………21
3-3-1 Detector Test and Calibration……………………………21
3-3-2 Measurements with phantoms…………………………………23
3-4 The Geant4 Monte Carlo Simulation…………………………25
Chapter 4 Data Analysis and Discussion of Result……………29
4-1 The Geant4 Simulated Result and Verification……………29
4-1-1 The Simulated Beam Energy by Geant4 Monte Carlo Software…………………………………………………………………29
4-1-2 The Fluence and Range Straggling…………………………31
4-1-3 General Discussion……………………………………………32
4-2 The Analysis of Image Resolution……………………………34
4-2-1 The Procedure of Image Resolution………………………34
4-2-2 General Discussion……………………………………………37
4-3 The Procedure of Algorithmic Method………………………38
4-3-1 The Median Filter Algorithmic Method……………………38
4-3-2 The Flood Fill Algorithmic Method………………………39
4-4 Radiation Dose and Unit………………………………………40
4-4-1 Radiation Dose Unit…………………………………………40
4-4-2 Radiation Dose Equivalent…………………………………40
4-5 The Selection of Residual Object in Image by Algorithmic Method…………………………………………………43
4-5-1 The Procedure of Image Selection…………………………43
4-5-2 General Discussion……………………………………………47
Chapter 5 Summary……………………………………………………49
Reference ………………………………………………………………51
參考文獻 [1] http://mhlclinics.com/proton_therapy.html
[2] http://project-aqua.web.cern.ch/project-aqua/
[3] Ervin B. Podgorsak, "Radiation Physics for Medical Physicists", P.247, Spriger, New York, (2010).
[4] Brian J McParland,"Nuclear Medicine Radiation Dosimetry: Advanced Theoretical Principles", P.316, New York,(2011).
[5] Frank H. Attix, "Introduction to Radiological Physics and Radiation Dosimetry.", P, John Wiley & Sons Inc., New York, (1986).
[6] James Edward Turner, "Atoms, Radiation, and Radiation Protection", John Wiley & Sons Inc., New York, (1986).
[7]http://jicru.oxfordjournals.org/content/7/2/11/F4.expansion
[8] U. Amaldi et al ,"Construction, test and operation of a proton range radiography system",Nucl. Instr. and Meth. A, 629 (2010), p. 337.
[9] M. Beyzadeoglu, et al, "Basic Radiation Oncology", Spiger, New York, (2010).
[10] A. Bressan et al.,"Two-dimensional readout of GEM detectors",Nucl.Instr. and Meth. A, 425 (1999), p. 254
[11] Stefaan Tavernier,"Experimental Techniques in Nuclear and Particle Physics",P.137, Spriger, New York, (2010).
[12] Syed Naeem Ahmed "Physics and Engineering of Radiation Detection", P.339, ELSEVIER, (2007).
[13] D. Watts, et al., "A Proton Range Telescope for Quality Assurance in Hadrontherapy", Proc. IEEE Nuclear Science Symposium (2009).
[14] Geant4 Collaboration, "Geant4 User’’s Guide for Application Developers", 2007.
[15] G. Dougherty, "Digital Image Processing for Medical Applications", Cambridge, 2009.
[16] Rafael C.Ganzalez, etc, "Digital Image Processing 2nd",Prentice Hall, 2002
[17] Harald Paganetti,," PROTON THERAPY PHYSICS",CRC Press, 2011
指導教授 張元翰(Yuan-Hann Chang) 審核日期 2012-7-26
推文 facebook   plurk   twitter   funp   google   live   udn   HD   myshare   reddit   netvibes   friend   youpush   delicious   baidu   
網路書籤 Google bookmarks   del.icio.us   hemidemi   myshare   

若有論文相關問題,請聯絡國立中央大學圖書館推廣服務組 TEL:(03)422-7151轉57407,或E-mail聯絡  - 隱私權政策聲明