博碩士論文 983203071 詳細資訊


姓名 古武昇(Wu-Sheng Gu)  查詢紙本館藏   畢業系所 機械工程學系
論文名稱 全場光強差動式表面電漿共振偵測技術
(Intensity differential surface plasmon resonance technique with full-field detection)
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摘要(中) 本論文以差動偵測技術配合表面電漿共振技術,再結合CCD擷取影像資訊,提出一套可偵測一平面折射率分布的「全場光強差動式表面電漿共振偵測技術」。本研究利用差動偵測的概念,除了可有效消除光源強度浮動和背景光雜訊對訊號的影響外,並且可提升共振光強分析式系統對於折射率的靈敏度,以改善一般光強分析式系統的缺點。
對於實驗結果作分析後,可得知本系統光強差動訊號對於折射率的靈敏度為1.35×10^2 (1/RIU),而光強差動訊號之解析度為0.0016,由前面兩者可算出本系統對於折射率的解析度為1.2×10^-5 RIU。本系統具有成本低、即時量測、靈敏度和解析度高的優點,若能實際將此技術使用於生物分子陣列晶片的偵測,對於生醫檢測領域將是一大貢獻。
摘要(英) An intensity differential surface plasmon resonance (SPR) technique with full-field detection is proposed. In this study, we combine the differential detection technique, SPR technique and CCD camera to detect the refractive index variation of the testing sample. The system can not only reduce the influence of laser source fluctuation and ambient noise, but also improve the measurement sensitivity and resolution, to improve the defect of common resonance light intensity.
The experimental results demonstrate that the sensitivity of the system is 1.35×10^2 (1/RIU) and the resolution of intensity differential signal is 0.0016, so the resolution of refractive index is 1.2×10^-5 RIU. The system has the advantages of low cost, real-time detection, higher sensitivity and resolution. If the system can be applied to the biological molecule array, it will have large contribution for biomedical testing.
關鍵字(中) ★ 全場光強
★ 差動偵測
★ 表面電漿共振
關鍵字(英) ★ full-field detection
★ differential detection
★ surface plasmon resonance
論文目次 摘要i
Abstractii
誌謝iii
目錄iv
圖目錄vi
表目錄viii
第一章 緒論1
1-1 研究背景1
1-2 文獻回顧1
1-3 研究動機、目的與方法7
1-4 論文架構8
第二章 基礎理論9
2-1 表面電漿共振原理9
2-1-1 表面電漿共振理論推導9
2-1-2 激發表面電漿波的方式11
2-1-3 Kretschmann架構下的光強反射率推導13
2-2 反射光強差動偵測原理18
2-3 小結21
第三章 實驗架構22
3-1 感測器參數設計 22
3-2 感測器機構設計 25
3-3 整體系統架構30
3-4 程式設計33
3-4-1 第一部分:角度掃描33
3-4-2 第二部分:光強差動訊號擷取35
3-5 小結37
第四章 結果與討論38
4-1 實驗準備38
4-1-1 製作表面電漿共振感測器38
4-1-2 待測物42
4-1-3 全場量測感測片42
4-2 第一部分實驗:單點量測43
4-2-1 交叉通入氣體實驗44
4-2-2 階梯通入氣體實驗48
4-3 第二部分實驗:全場量測49
4-4 第三部分實驗:消除光源強度浮動實驗56
4-5 系統對折射率之解析度分析60
4-5-1 光強差動訊號之解析度60
4-5-2 系統對於折射率之靈敏度60
4-5-3 系統對於折射率之解析度61
4-6 系統誤差分析61
4-6-1 共振角誤差61
4-6-2 光強差動訊號誤差62
4-7 小結63
第五章 結論與未來展望64
參考文獻 65
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指導教授 李朱育(Ju-Yi Lee) 審核日期 2012-1-20
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