整合EPnP及導引器械之C-arm影像輔助脊椎手術用導引系統

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陳冠君(Kuan-Chun Chen) 查詢紙本館藏

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機械工程學系

論文名稱

整合EPnP及導引器械之C-arm影像輔助脊椎手術用導引系統

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摘要(中)

椎莖螺釘手術具有高危險性，手術中醫師不斷藉由拍攝C-arm X光影像以避免失誤，然高輻射劑量危害到病患以及醫護人員的健康，且徒手進行手術很仰賴醫師的經驗及手感，經驗不足的醫師其成功率相對的低很多。影像輔助脊椎手術導引系統可協助解決鑽孔定位的問題，但已知的市售導航系統都配備光學式定位裝置，價格昂貴使得導航系統不易普及化，因此發展一成本低兼具鑽孔導引支撐功能的脊椎手術用導引系統是有其重要性。
本研究以實驗室既有的C-arm影像輔助椎莖螺釘植入手術用的導引系統為基礎，以高效率透視N點攝影機姿態估計方法（EPnP）取代光學式定位器的定位功能，結合特徵樣板上的特徵點影像辨識及影像中心計算，求得AP及LA方向C-arm影像與特徵樣板的座標轉換關係，並於AP及LA影像上規劃椎莖的鑽孔進入點與結束點，再利用雙角度攝影空間定位技術計算出鑽孔路徑的空間方向，將該鑽孔路徑方位轉換至導引輔具座標系上，並調整導引輔具上的鑽孔導槽方向與鑽孔路徑重合，醫師即可依循該導槽進行椎莖鑽孔手術。可跨接在手術台兩側的鑽孔導引輔具具有四自由度，兩個平移自由度用以定位鑽孔導槽位置，另兩個旋轉自由度則定位鑽孔導槽方向。
實驗以一含雙尖點的器械模擬鑽孔路徑，該兩尖點分別用來模擬鑽孔進入點以及結束點的真實空間位置。幾次實驗結果顯示進入點的位置誤差為2.92±0.76mm，結束點的位置誤差為3.41±0.99mm，方向誤差為0.73±0.33度。

摘要(英)

Pedicle screw insertion is a high risk operation. Also free-hand operation is highly relied on surgeon’s clinic experience and hand feeling. The operation success rate is relatively lower for inexperienced surgeons. Image assisted surgical navigation system for spine surgery can provide position assistance of drilling. Commercially available navigation systems are equipped with an optical tracker. The high price of the navigation system makes it not easy to popularize. Therefore, development of a low cost navigation system with drill guide device for spine surgery is highly recommended.
This study is based on C-arm image assisted surgical navigation system for pedicle screw insertion developed in our laboratory. Efficient perspective-n-point camera pose estimation (EPnP) method is applied to replace the optical tracker to estimate 3D pose of the featuring phantom. The transformation matrix between the AP/LA view C-arm image frames and featuring phantom frame can be determined by EPnP method with feature point image recognition and image center position calculation. Then the drill path defined by the entry point and end point selected on both AP and LA images can be determined by bi-plane method. By adjusting the guide slot of drill guide device to be coaxial with the planned drill path, then the surgeon can safely drill the pedicle just by following the guide slot. The four- degree-of-freedom drill guide device can be mounted on both sides of the operating table. Two translational degrees of freedom are for positioning the center of the guiding slot while the other two rotational degrees of freedom are for positioning the direction of the guide slot.
In the experiment, a device with two cusps is used to simulate the drilling path. The two cusps are used to simulate the entry point and end point of drilling path. Several experimental results show that the position errors of the entry and end points are 2.92±0.76mm and 3.41±0.99mm respectively, and the direction error is 0.73±0.33°.

關鍵字(中)

★ C-arm影像
★ 手術導引
★ 脊椎手術
★ 高效率透視N點攝影機姿態估計

關鍵字(英)

★ C-arm image
★ surgical navigation
★ spine surgery
★ EPnP

論文目次

摘要 I
Abstract II
目錄 III
表目錄 V
圖目錄 VI
第1章緒論 1
1-1 研究動機 1
1-2 文獻回顧 3
1-3 研究方法簡介 6
第2章研究方法 8
2-1 座標系統與座標系統間之轉換關係 8
2-2 C-arm系統 9
2-2-1 成像原理 9
2-2-2 影像畸變 10
2-2-3 影像畸變校正 10
2-2-4 C-arm投影中心與C-arm有X光理想發射源 12
2-2-5 攝影機座標系定義 12
2-3 C-arm影像輔助手術導引系統 13
2-3-1 影像輔助手術導引系統概述 13
2-3-2 植入椎莖螺釘之C-arm影像輔助手術導引系統 14
2-4 攝影機姿態估計 18
2-4-1 單點透視投影模型 18
2-4-2 C-arm攝影機投影模型 20
2-4-3 攝影機姿態估計演算法 21
2-4-4 特徵樣板設計 25
2-4-5 標記與標記物影像的對應關係 27
2-4-6 多角度攝影空間定位技術 28
2-5 研究方法總結 32
第3章實驗結果與討論 33
3-1 攝影機姿態估計演算法評估實驗 33
3-1-1 驗證方法 33
3-1-2 EPnP演算法誤差評估實驗 35
3-2 影像校正器評估實驗 40
3-3 特徵樣板與導引輔具設計 49
3-3-1 特徵樣板設計 49
3-3-2 導引輔具設計 50
3-4 整體導引系統精度驗證實驗 52
第4章結論與未來展望 66
參考文獻 68

參考文獻

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指導教授

曾清秀(Ching-Shiow Tseng)

審核日期

2015-7-28

推文