骨板與骨釘之參數模型應用於股骨骨折術前規劃

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高漢元(Han-Yuan Gao) 查詢紙本館藏

畢業系所

機械工程學系

論文名稱

骨板與骨釘之參數模型應用於股骨骨折術前規劃
(A parametric screw-plate model for the preoperative planning of fractured femur surgery)

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摘要(中)

目前臨床上對於不同斷裂部位的骨折，發展出對應的樣式骨板與骨釘系統作為固定治療方式，為了解骨板於使用上的力學行為，並且給予骨科醫師作為選擇植入物之依據，因此本研究包含植體之骨板與骨釘於骨組織中的解析解推導，考慮植體於骨骼系統內的簡化模型承受簡單外力形式；使用COMSOL Multiphysics軟體分析含植體之骨組織有限元素模擬技術建立與驗證，探討植體及骨頭中的應力值與應變值。另外，也針對實驗樣品建立有限元素模型，計算植體結構強度，探討骨骼、骨板與骨釘的變形、應力與應變，此結果將作為植體選擇與鎖固分析的依據。本研究藉由COMSOL App建立器(Application Builder)分析不同骨板與骨釘的參數設定所呈現的應力及應變，可作為植體的材料選擇、螺釘數量的選擇及接觸式或非接觸式骨板的選擇；而從實際Sawbones模型得知螺釘的數目與位置，會影響骨板的應力分佈，可提供醫師手術前規劃的初步參考資訊。

摘要(英)

At present, several types of implant (plate and screws) have been developed for the corresponding bone fractures at different sites. In order to understand the mechanical behavior of bone plate and to give surgeons some suggestions of selecting implants, this study includes the following aspects. The simplified model of bone-implant system subjected to an eccentric axial compression was derived in analytical form. In addition, the stress and strain in bone and implant were investigated using COMSOL Multiphysics software. Furthermore, the computed tomography (CT)-based finite element model was established to calculate the strength of the implant as well as the deformation, stress and strain of the bone, plate and screws. These results can serve as guidance for the selecting implant. This study also uses COMSOL Application Builder to analyze the stress and strain of a screw-plate fixation for different parameters such as the material of the implant, the number of screws and contact or non-contact plate. The CT-based model reveals the number and location of screws affected the stress distribution of the bone plate. It can provide preliminary reference information for clinicians before surgery.

關鍵字(中)

★ 骨板
★ 股骨骨折
★ 有線元素法
★ 簡化模型
★ Application Builder
★ 實際Sawbones模型

關鍵字(英)

★ bone plate
★ femur fractured
★ finite element analysis
★ simplified model
★ Application Builder
★ CAD of experimental model

論文目次

目錄
摘要 i
Abstract ii
誌謝 iii
目錄 iv
圖目錄 vii
表目錄 xii
符號說明 xiii
第一章緒論 1
1.1 前言 1
1.2 文獻回顧 2
1.3 研究目的與方法 18
1.3.1 研究目的 18
1.3.2 研究方法 19
1.4 論文架構 20
第二章公式推導 21
2.1 前言 21
2.2 選擇截面與假設 22
2.2.1 對稱梁：對單一材料的梁施加軸向負載 24
2.2.2 對稱梁：單一材料梁的彎曲 25
2.2.3 對稱梁：對三種材料的梁施加軸向負載 27
2.2.4 對稱梁：三種材料梁的彎曲 29
2.3 植體與骨頭系統的力學行為 31
2.3.1 應力於骨植入系統之骨組織中的解析解推導過程 32
2.3.2 應力於骨植入系統之植體中的解析解推導過程 39
第三章建立模型、材料及方法與應用App 43
3.1 前言 43
3.2 建立簡化模型 44
3.3 建立實際Sawbones模型 54
3.3.1 長骨實體模型 54
3.3.2 骨板及骨釘實體模型 55
3.4 應用App 61
第四章結果與討論 65
4.1 前言 65
4.2 簡化模型FEA及比較結果 65
4.2.1 第一種簡化模型應力分析結果 66
4.2.2 第二種簡化模型應力分析結果 70
4.2.3 第三種簡化模型應用App分析結果 73
4.3 實際Sawbones模型分析結果 80
第五章結論與未來展望 85
5.1 結論 85
5.2 未來展望 87
參考文獻 89

參考文獻

[1] T. Miclau and R. Martin, "The evolution of modern plate osteosynthesis." Injury, 28, A3-A6, 1997.
[2] S. Mehmood, U. Ansari, M. N. Ali and N. F. Rana, "Internal fixation: An evolutionary appraisal of methods used for long bone fractures." International Journal of Biomedical and Advance Research, 5, 3, 142-149, 2014.
[3] J. Schatzker, "Osteosynthesis in trauma." International Orthopaedics, 20, 4, 244-252, 1996.
[4] R. M. Greenhagen, A. R. Johnson and A. Joseph, "Internal fixation: a historical review." Clinics in podiatric medicine and surgery, 28, 4, 607-618, 2011.
[5] S. R. Lathan, "Dr. Halsted at Hopkins and at High Hampton." Proceedings (Baylor University. Medical Center), 23, 1, 33, 2010.
[6] W. A. Lane, "Some remarks on the treatment of fractures." British medical journal, 1, 1790, 861, 1895.
[7] H. K. Uhthoff, P. Poitras and D. S. Backman, "Internal plate fixation of fractures: short history and recent developments." Journal of Orthopaedic Science, 11, 2, 118-126, Aug 2006.
[8] L. F. Peltier, Fractures: A History and Iconography of Their Treatment. Norman Pub., 1990.
[9] R. Danis, Théorie et pratique de l′ostéosynthèse. Masson, Paris, 1949.
[10] A. E. Freeland, M. E. Jabaley and J. L. Hughes, Stable Fixation of the Hand and Wrist. Springer New York, 2012.
[11] F. Povacz, Geschichte der Unfallchirurgie. Springer Berlin Heidelberg, 2008.
[12] P. Vichard and E. Gagneux, "Il ya 100 ans: les premiers pas de l’ostéosynthèse des fractures." Histoire des sciences médicales, 29, 2-1995, 1995.
[13] B. D. Browner, J. B. Jupiter, C. Krettek and P. A. Anderson, Skeletal Trauma. Elsevier Health Sciences, 2014.
[14] S. M. Perren and J. S. Buchanan, "Basic concepts relevant to the design and development of the point contact fixator (PC-Fix)." Injury, 26, B1-B4, 1995.
[15] A. Remiger, M. Predieri, S. Tepic and S. Perren, "Internal Fixation Using the Point Contact Plate: An In-Vivo Study in Sheep." Journal of Orthopaedic Trauma, 7, 2, 176, 1993.
[16] S. Tepic, A. R. Remiger, K. Morikawa, M. Predieri and S. M. Perren, "Strength recovery in fractured sheep tibia treated with a plate or an internal fixator: an experimental study with a two-year follow-up." Journal of orthopaedic trauma, 11, 1, 14-23, 1997.
[17] M. Schuetz, M. Müller, C. Krettek, D. Höntzsch, P. Regazzoni, R. Ganz and N. Haas, "Minimally invasive fracture stabilization of distal femoral fractures with the LISS: A prospective multicenter study results of a clinical study with special emphasis on difficult cases." Injury, 32, 48-54, 2001.
[18] S. Tepic and S. Perren, "The biomechanics of the PC-Fix internal fixator." Injury, 26, B5-B10, 1995.
[19] P. Schandelmaier, C. Stephan, N. Reimers and C. Krettek, "LISS-Osteosynthese von distalen Femurfrakturen." Trauma und Berufskrankheit, 1, 4, 392-397, 1999.
[20] R. Frigg, "Locking compression plate (LCP). An osteosynthesis plate based on the dynamic compression plate and the point contact fixator (PC-Fix)." Injury, 32, 63-66, 2001.
[21] K. Tayton, C. Johnson-Nurse, B. McKibbin, J. Bradley and G. Hastings, "The use of semi-rigid carbon-fibre-reinforced plastic plates for fixation of human fractures. Results of preliminary trials." Bone and Joint Journal, 64-B, 1, 105-111, 1982.
[22] C. Igna and L. Schuszler, "Current concepts of internal plate fixation of fractures." Bulletin UASVM, Veterinary Medicine, 67, 2, 118-124, 2010.
[23] P. Schandelmaier, A. Partenheimer, B. Koenemann, O. Grün and C. Krettek, "Distal femoral fractures and LISS stabilization." Injury, 32, 55-63, 2001.
[24] D. L. Miller and T. Goswami, "A review of locking compression plate biomechanics and their advantages as internal fixators in fracture healing." Clinical Biomechanics, 22, 10, 1049-1062, 2007.
[25] C. Alemdar, I. Azboy, R. Atic, E. Ozkul, M. Gem and A. Kapukaya, "Management of infectious fractures with “Non-Contact Plate”(NCP) method." Acta Orthop Belg, 81, 3, 523-529, 2015.
[26] G. S. Leventhal, "Titanium, a metal for surgery." J Bone Joint Surg Am, 33, 2, 473-474, 1951.
[27] N. Patil, K. Lee and S. B. Goodman, "Porous tantalum in hip and knee reconstructive surgery." Journal of Biomedical Materials Research Part B: Applied Biomaterials, 89, 1, 242-251, 2009.
[28] B. Gasser, "About composite materials and their use in bone surgery." Injury, 31, D48-D53, 2000.
[29] B. R. Simon, S. L. Y. Woo, G. M. Stanley, S. R. Olmstead, M. P. McCarty, G. F. Jemmott and W. H. Akeson, "Evaluation of one-, two-, and three-dimensional finite element and experimental models of internal fixation plates." Journal of Biomechanics, 10, 2, 79-86, 1977/01/01 1977.
[30] K. Ramakrishna, I. Sridhar, S. Sivashanker, K. S. Khong and D. N. Ghista, "Design of fracture fixation plate for necessary and sufficient bone stress shielding." JSME International Journal Series C Mechanical Systems, Machine Elements and Manufacturing, 47, 4, 1086-1094, 2004.
[31] K. Ramakrishna, I. Sridhar, S. Sivashanker, V. Ganesh and D. Ghista, "Analysis of an internal fixation of a long bone fracture." Journal of Mechanics in Medicine and Biology, 5, 01, 89-103, 2005.
[32] D. Ghista, Applied Biomedical Engineering Mechanics. CRC Press, 2008.
[33] J. Wieding, R. Souffrant, A. Fritsche, W. Mittelmeier and R. Bader, "Finite element analysis of osteosynthesis screw fixation in the bone stock: an appropriate method for automatic screw modelling." PLoS One, 7, 3, e33776, 2012.
[34] T. P. James and B. A. Andrade, "Modeling Bicortical Screws Under a Cantilever Bending Load." Journal of biomechanical engineering, 135, 12, 124502, 2013.
[35] C. Avery, P. Bujtár, J. Simonovics, T. Dézsi, K. Váradi, G. K. Sándor and J. Pan, "A finite element analysis of bone plates available for prophylactic internal fixation of the radial osteocutaneous donor site using the sheep tibia model." Medical engineering & physics, 35, 10, 1421-1430, 2013.
[36] C. M. E. Avery, M. Skidmore, A. Peden and J. Pan, "Biomechanical study of a unilocking T-plate system for prophylactic internal fixation of the radial osteocutaneous donor site using the sheep tibia model." Oral Oncology, 47, 4, 268-273, 4 2011.
[37] P. Kenedi and L. L. Vignoli, "Ostheosynthesis plate: analytical and finite element approaches." XXIV Brazilian Congress of Biomedical Engineering—CBEB, 2014.
[38] J. M. Gere and S. P. Timoshenko, Mechanics of materials. PWS Pub Co., 1997.
[39] J. Cordey, S. Perren and S. Steinemann, "Stress protection due to plates: myth or reality? A parametric analysis made using the composite beam theory." Injury, 31, 178838791-13, 2000.
[40] M. Pendergast and R. Rusovici, "A finite element parametric study of clavicle fixation plates." International journal for numerical methods in biomedical engineering, 31, 6, 2015.
[41] A. G. Tsai, T. Ashworth and O. Akkus, "Strength of Materials Based Prediction of Critical Stresses at the Proximal Femur: Validation by Finite Element Analysis." ASME 2013 Summer Bioengineering Conference, V01AT09A006; 2 pages, Sunriver, Oregon, USA, June 2013.
[42] H. M. Frost, "Wolff′s Law and bone′s structural adaptations to mechanical usage: an overview for clinicians." The Angle Orthodontist, 64, 3, 175-188, 1994.
[43] G. Hastings, "Biomedical engineering and materials for orthopaedic implants." Journal of physics E: Scientific instruments, 13, 6, 599, 1980.
[44] K. A. Egol, E. N. Kubiak, E. Fulkerson, F. J. Kummer and K. J. Koval, "Biomechanics of locked plates and screws." Journal of orthopaedic trauma, 18, 8, 488-493, 2004.
[45] L. E. Claes, C. A. Heigele, C. Neidlinger-Wilke, D. Kaspar, W. Seidl, K. J. Margevicius and P. Augat, "Effects of mechanical factors on the fracture healing process." Clinical orthopaedics and related research, 355, S132-S147, 1998.
[46] S. Perren, "Physical and biological aspects of fracture healing with special reference to internal fixation." Clinical orthopaedics and related research, 138, 175-196, 1979.
[47] H. Gray and W. H. Lewis, Anatomy of the Human Body. Lea & Febiger, 1918.
[48] V. K. Ganesh, K. Ramakrishna and D. N. Ghista, "Biomechanics of bone-fracture fixation by stiffness-graded plates in comparison with stainless-steel plates." Biomed Eng Online, 4, 46, Jul 2005.
[49] G. Mohammad, H. Zamanian, B. Marzban and S. Amoozegar, "Investigation of the Stress Distribution in a Bone Due to Screws Pretensions of the Bone Plate." Dep. of Biomedical Eng., Amirkabir University of Tech, 2013.
[50] S. Benli, S. Aksoy, H. Havitcioglu and M. Kucuk, "Evaluation of bone plate with low-stiffness material in terms of stress distribution." J Biomech, 41, 15, 3229-35, Nov 2008.
[51] H. Fouad, "Assessment of function-graded materials as fracture fixation bone-plates under combined loading conditions using finite element modelling." Med Eng Phys, 33, 4, 456-63, May 2011.
[52] H. Fouad, "Effects of the bone-plate material and the presence of a gap between the fractured bone and plate on the predicted stresses at the fractured bone." Med Eng Phys, 32, 7, 783-9, Sep 2010.
[53] T. P. Rüedi and W. M. Murphy, AO Principles of Fracture Management. AO Publishing, 2000.
[54] 王明暄, 電腦輔助長骨創傷手術骨板置放與模擬, 國立中央大學, 碩士論文, 民國102年.
[55] R. Compton and J. Mason, Fatigue Strength of Zimmer Periarticular Locking Plates, I. Zimmer Biomet Holdings, 2009.
[56] L. D. Zardiackas, "Stainless Steels for Implants." Wiley Encyclopedia of Biomedical Engineering, 2006.
[57] R. Hibbeler, Statics and Mechanics of Materials. Pearson Education Canada, 2014.
[58] W. B. Hildreth, Case Studies in Public Budgeting and Financial Management, Revised and Expanded. Taylor & Francis, 2003.
[59] D. L. Waller, Operations Management: A Supply Chain Approach. Thomson Learning, 2003.
[60] S. Nasr, S. Hunt and N. A. Duncan, "Effect of screw position on bone tissue differentiation within a fixed femoral fracture." Journal of Biomedical Science and Engineering, 6, 12, 71-83, 2013.

指導教授

鍾禎元(Chen-Yuan Chung)

審核日期

2017-7-6

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