| 摘要(英) |
Since 1982, cancer has been the top ten cause of death among Chinese people. Today, radiation therapy is considered a viable non-invasive cancer treatment, so about 50% of cancer patients receive radiation therapy during treatment, and radiation therapy includes photon therapy and proton therapy. Recent advances in proton therapy have provided a highly uniform and high-dose-rate of precise treatment for the treatment of tumors. To achieve this goal, a better quality assurance program is needed to ensure treatment quality. Therefore, the starting point of the detector design discussed in this paper is the application of proton therapy.
The XY strip detector studied in this paper is characterized by a large area of induction receiving surface (345.44 × 345.44 mm2), high spatial resolution ( < 60μm), high dynamic response range (20 bits, ADC reachable 1,048,576) with high sensitivity (50 fC), and has flexible operation options such as integration time and charge accumulation range. In addition, the LabVIEW program′s human-machine interface is used to collect experimental data and monitor beam changes in real time. Therefore, the existing hardware structure, electronic components, and operation interface of the XY strip detector can meet the current hospital proton beam-related quality assurance operations.
The detector can be used to understand the performance of the detector when it is used in the daily inspection of the pen tip scanning beam parameters of the hospital. The overall resolution is better than that of the current hospital. In the proton beam patient dose test, the high signal dynamic range and signal change rate of the detector can clearly distinguish the absorbed dose distribution when the beam is incident with different energies if it can be supplemented with appropriate blocking power and simulation. Program to reconstruct the three-dimensional dose distribution at different depths and locations in patients. If patient dose protection is implemented, it is expected to shorten the test time to less than 5 minutes, which will bring significant efficiency to patient dose assurance. And quality improvement. This result shows that the detector is suitable for hospital daily proton beam warranty and patient dose warranty.
When the new proton therapy in Linkou Chang Gung Hospital uses a pen tip beam scan, the beam varies greatly in the lateral space. The detector can distinguish the slight difference in beam shape when the proton beam is incident at different positions. For more accurate calibration or to increase the beam dose rate, the detector can detect a rate of change of up to 10,000 times. At that time, the position and shape of the beam can be clearly recorded. According to this feature, the proton therapy device can be used in the future. The direction of quality assurance.
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