參考文獻 |
1. Ho, C.C., et al., Identification of ambient fine particulate matter components related to vascular dysfunction by analyzing spatiotemporal variations. Sci Total Environ, 2020. 719: p. 137243.
2. Ghio, A.J., M.S. Carraway, and M.C. Madden, Composition of air pollution particles and oxidative stress in cells, tissues, and living systems. J Toxicol Environ Health B Crit Rev, 2012. 15(1): p. 1-21.
3. Billet, S., et al., Ambient particulate matter (PM2.5): physicochemical characterization and metabolic activation of the organic fraction in human lung epithelial cells (A549). Environ Res, 2007. 105(2): p. 212-23.
4. Manisalidis, I., et al., Environmental and Health Impacts of Air Pollution: A Review. Front Public Health, 2020. 8: p. 14.
5. Xing, Y.F., et al., The impact of PM2.5 on the human respiratory system. J Thorac Dis, 2016. 8(1): p. E69-74.
6. Du, Y., et al., Air particulate matter and cardiovascular disease: the epidemiological, biomedical and clinical evidence. J Thorac Dis, 2016. 8(1): p. E8-E19.
7. Kaplan, G.G., et al., The inflammatory bowel diseases and ambient air pollution: a novel association. Am J Gastroenterol, 2010. 105(11): p. 2412-9.
8. Ananthakrishnan, A.N., et al., Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis. Inflamm Bowel Dis, 2011. 17(5): p. 1138-45.
9. Mutlu, E.A., et al., Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome. Environ Pollut, 2018. 240: p. 817-830.
10. Gwinn, M.R. and V. Vallyathan, Respiratory burst: role in signal transduction in alveolar macrophages. J Toxicol Environ Health B Crit Rev, 2006. 9(1): p. 27-39.
11. Sauer, H., M. Wartenberg, and J. Hescheler, Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem, 2001. 11(4): p. 173-86.
12. Morgan, M.J. and Z.G. Liu, Crosstalk of reactive oxygen species and NF-kappaB signaling. Cell Res, 2011. 21(1): p. 103-15.
13. Yun, H.R., et al., Roles of Autophagy in Oxidative Stress. Int J Mol Sci, 2020. 21(9).
14. Rao, X., et al., Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways. Antioxid Redox Signal, 2018. 28(9): p. 797-818.
15. Valavanidis, A., et al., Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanisms. Int J Environ Res Public Health, 2013. 10(9): p. 3886-907.
16. Kensler, T.W., N. Wakabayashi, and S. Biswal, Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol, 2007. 47: p. 89-116.
17. Tkachev, V.O., et al., Synthetic water-soluble phenolic antioxidant regulates l-arginine metabolism in macrophages: a possible role of Nrf2/ARE. Biochemistry (Mosc), 2010. 75(5): p. 549-53.
18. Drechsler, Y., et al., Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes. J Immunol, 2006. 177(4): p. 2592-600.
19. Belcher, J.D., et al., Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. J Clin Invest, 2006. 116(3): p. 808-16.
20. Siegel, D., et al., NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. Mol Pharmacol, 2004. 65(5): p. 1238-47.
21. Siegel, D., et al., The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant. Mol Pharmacol, 1997. 52(2): p. 300-5.
22. Asher, G., et al., NQO1 stabilizes p53 through a distinct pathway. Proc Natl Acad Sci U S A, 2002. 99(5): p. 3099-104.
23. Asher, G., et al., Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1. Proc Natl Acad Sci U S A, 2002. 99(20): p. 13125-30.
24. Gilmore, T.D., Introduction to NF-kappaB: players, pathways, perspectives. Oncogene, 2006. 25(51): p. 6680-4.
25. Brasier, A.R., The NF-kappaB regulatory network. Cardiovasc Toxicol, 2006. 6(2): p. 111-30.
26. Hoffmann, A., et al., The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science, 2002. 298(5596): p. 1241-5.
27. Lawrence, T., The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb Perspect Biol, 2009. 1(6): p. a001651.
28. Liu, T., et al., NF-kappaB signaling in inflammation. Signal Transduct Target Ther, 2017. 2.
29. Harada, A., et al., Essential involvement of interleukin-8 (IL-8) in acute inflammation. J Leukoc Biol, 1994. 56(5): p. 559-64.
30. Vlahopoulos, S., et al., Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation. Blood, 1999. 94(6): p. 1878-89.
31. Brew, R., et al., Interleukin-8 as an autocrine growth factor for human colon carcinoma cells in vitro. Cytokine, 2000. 12(1): p. 78-85.
32. Mazzucchelli, L., et al., Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol, 1994. 144(5): p. 997-1007.
33. Landen, N.X., D. Li, and M. Stahle, Transition from inflammation to proliferation: a critical step during wound healing. Cell Mol Life Sci, 2016. 73(20): p. 3861-85.
34. Wang, J., et al., PM2.5 stimulated the release of cytokines from BEAS-2B cells through activation of IKK/NF-kappaB pathway. Hum Exp Toxicol, 2019. 38(3): p. 311-320.
35. Nam, H.Y., et al., The role of nitric oxide in the particulate matter (PM2.5)-induced NFkappaB activation in lung epithelial cells. Toxicol Lett, 2004. 148(1-2): p. 95-102.
36. Wang, J., et al., Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-kappaB signaling pathway. J Thorac Dis, 2017. 9(11): p. 4398-4412.
37. Li, X., et al., Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution. Adv Sci (Weinh), 2019. 6(11): p. 1900180.
38. Yu, J.S. and W. Cui, Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination. Development, 2016. 143(17): p. 3050-60.
39. Hemmings, B.A. and D.F. Restuccia, PI3K-PKB/Akt pathway. Cold Spring Harb Perspect Biol, 2012. 4(9): p. a011189.
40. Kumar, B., et al., Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res, 2008. 68(6): p. 1777-85.
41. Ojeda, L., et al., Critical role of PI3K/Akt/GSK3beta in motoneuron specification from human neural stem cells in response to FGF2 and EGF. PLoS One, 2011. 6(8): p. e23414.
42. Liu, R., et al., PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death Dis, 2020. 11(9): p. 797.
43. Bai, D., L. Ueno, and P.K. Vogt, Akt-mediated regulation of NFkappaB and the essentialness of NFkappaB for the oncogenicity of PI3K and Akt. Int J Cancer, 2009. 125(12): p. 2863-70.
44. Kennedy, S.G., et al., The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev, 1997. 11(6): p. 701-13.
45. Muilenburg, D., et al., Role of autophagy in apoptotic regulation by Akt in pancreatic cancer. Anticancer Res, 2014. 34(2): p. 631-7.
46. Atillasoy, E. and P.R. Holt, Gastrointestinal proliferation and aging. J Gerontol, 1993. 48(2): p. B43-9.
47. Lee, D.C., et al., Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells. Toxicol Lett, 2020. 333: p. 33-41.
48. Baehrecke, E.H., Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol, 2005. 6(6): p. 505-10.
49. Kondo, Y., et al., The role of autophagy in cancer development and response to therapy. Nat Rev Cancer, 2005. 5(9): p. 726-34.
50. Cordani, M., et al., Interplay between ROS and Autophagy in Cancer and Aging: From Molecular Mechanisms to Novel Therapeutic Approaches. Oxid Med Cell Longev, 2019. 2019: p. 8794612.
51. Maiuri, M.C., et al., Autophagy regulation by p53. Curr Opin Cell Biol, 2010. 22(2): p. 181-5.
52. Glick, D., S. Barth, and K.F. Macleod, Autophagy: cellular and molecular mechanisms. J Pathol, 2010. 221(1): p. 3-12.
53. Zheng, K., et al., Selective Autophagy Regulates Cell Cycle in Cancer Therapy. Theranostics, 2019. 9(1): p. 104-125.
54. Qian, M., X. Fang, and X. Wang, Autophagy and inflammation. Clin Transl Med, 2017. 6(1): p. 24.
55. Soussi, H., K. Clement, and I. Dugail, Adipose tissue autophagy status in obesity: Expression and flux--two faces of the picture. Autophagy, 2016. 12(3): p. 588-9.
56. Deng, X., et al., PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. Toxicol In Vitro, 2013. 27(6): p. 1762-70.
57. Haq, S., et al., Autophagy: roles in intestinal mucosal homeostasis and inflammation. J Biomed Sci, 2019. 26(1): p. 19.
58. Zhang, W., et al., Source diagnostics of polycyclic aromatic hydrocarbons in urban road runoff, dust, rain and canopy throughfall. Environ Pollut, 2008. 153(3): p. 594-601.
59. Ravindra, K., E. Wauters, and R. Van Grieken, Variation in particulate PAHs levels and their relation with the transboundary movement of the air masses. Sci Total Environ, 2008. 396(2-3): p. 100-10.
60. Pies, C., et al., Characterization and source identification of polycyclic aromatic hydrocarbons (PAHs) in river bank soils. Chemosphere, 2008. 72(10): p. 1594-1601.
61. De La Torre-Roche, R.J., W.Y. Lee, and S.I. Campos-Diaz, Soil-borne polycyclic aromatic hydrocarbons in El Paso, Texas: analysis of a potential problem in the United States/Mexico border region. J Hazard Mater, 2009. 163(2-3): p. 946-58.
62. Akyuz, M. and H. Cabuk, Gas-particle partitioning and seasonal variation of polycyclic aromatic hydrocarbons in the atmosphere of Zonguldak, Turkey. Sci Total Environ, 2010. 408(22): p. 5550-8.
63. Oliveira, C., et al., Size distribution of polycyclic aromatic hydrocarbons in a roadway tunnel in Lisbon, Portugal. Chemosphere, 2011. 83(11): p. 1588-96.
64. Katsoyiannis, A., E. Terzi, and Q.Y. Cai, On the use of PAH molecular diagnostic ratios in sewage sludge for the understanding of the PAH sources. Is this use appropriate? Chemosphere, 2007. 69(8): p. 1337-9.
65. Tobiszewski, M. and J. Namiesnik, PAH diagnostic ratios for the identification of pollution emission sources. Environ Pollut, 2012. 162: p. 110-9.
66. Forrester, S.J., et al., Reactive Oxygen Species in Metabolic and Inflammatory Signaling. Circ Res, 2018. 122(6): p. 877-902.
67. Wu, Y.T., et al., Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem, 2010. 285(14): p. 10850-61.
68. Wang, W., et al., Exposure to concentrated ambient PM2.5 alters the composition of gut microbiota in a murine model. Part Fibre Toxicol, 2018. 15(1): p. 17.
69. Vignal, C., et al., Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon. Part Fibre Toxicol, 2017. 14(1): p. 46.
70. Xu, F., et al., Necroptosis Contributes to Urban Particulate Matter-Induced Airway Epithelial Injury. Cell Physiol Biochem, 2018. 46(2): p. 699-712.
71. Mariani, F., P. Sena, and L. Roncucci, Inflammatory pathways in the early steps of colorectal cancer development. World J Gastroenterol, 2014. 20(29): p. 9716-31.
72. Chen, Y., et al., microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway. Oncotarget, 2016. 7(27): p. 41306-41319.
73. Suman, S., et al., Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells. Oncotarget, 2016. 7(12): p. 13854-64.
74. Mundi, P.S., et al., AKT in cancer: new molecular insights and advances in drug development. Br J Clin Pharmacol, 2016. 82(4): p. 943-56.
75. Wu, Y., et al., The role of autophagy in maintaining intestinal mucosal barrier. J Cell Physiol, 2019. 234(11): p. 19406-19419.
76. Shao, B.Z., et al., The Role of Autophagy in Inflammatory Bowel Disease. Front Physiol, 2021. 12: p. 621132.
77. Hu, X., et al., ATF4 Deficiency Promotes Intestinal Inflammation in Mice by Reducing Uptake of Glutamine and Expression of Antimicrobial Peptides. Gastroenterology, 2019. 156(4): p. 1098-1111.
78. Varma, M., et al., Cell Type- and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn′s Disease Risk Variant T300A. J Immunol, 2020. 205(2): p. 414-424.
79. Wang, S.L., et al., Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease. Front Immunol, 2018. 9: p. 693. |