摘要： The formation of tetrahydrofurans from 2-hydroxyalkyl-oxirane or aziridine is reported. The 5-endo-tet cyclization/ring opening of aziridine proceeded smoothly to give tetrahydrofurans (THFs) under mild conditions. In contrast, the corresponding process of oxirane was unsuccessful and a sequence of S N 2 substitution/cyclization was required to form THFs. The application of the process to prepare ent -()-pachastrissamine is described. A 5- endo-tet cyclization/ring opening of aziridine gives THF. 出版日期： 2013-07-24 資源來源： Royal Society of Chemistry 識別號： ISSN: 1477-0520 識別號： EISSN: 1477-0539 識別號： DOI: 10.1039/c3ob40797g
