摘要: For the first time, ∼100 nm zeolitic imidazolate framework-90 (ZIF-90) particles were produced by a water-alcohol-based system, taking advantage of viscosity effects using an optimized H 2 O/ tert -butanol/glycerol/PVP system. Furthermore, an in vitro cytotoxicity assay revealed the half-maximal effective concentration (EC 50 ) of ZIF-90 nanoparticles to be ∼92 μg ml −1 . 100 nm ZIF-90 nanoparticles with low cytotoxicity are obtained by utilizing glycerol for the control of viscosity effects in water-alcohol-based system. 出版日期: 2014-10-21 資源來源: Royal Society of Chemistry 識別號: EISSN: 2046-2069 識別號: DOI: 10.1039/c4ra10488a