Mineral substituted hydroxyapatite coatings deposited on nanoporous TiO2 modulate the directional growth and activity of osteoblastic cells†

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题名:	Mineral substituted hydroxyapatite coatings deposited on nanoporous TiO2 modulate the directional growth and activity of osteoblastic cells†
作者:	樋口亞紺;Govindaraj, Dharman;Rajan, Mariappan;Munusamy, Murugan A.;Higuchi, Akon
贡献者:	工學院化學工程與材料工程學系
关键词:	alkaline phosphatase;ambient temperature;biocompatibility;bone formation;calcium;coatings;energy-dispersive X-ray analysis;Fourier transform infrared spectroscopy;hydroxyapatite;magnesium;nanopores;orthopedics;osteoblasts;strength (mechanics);strontium;titanium;titanium dioxide;X-ray diffraction;X-ray photoelectron spectroscopy;zinc
日期:	2015-01-01
上传时间:	2026-04-21 14:32:19 (UTC+8)
出版者:	Royal Society of Chemistry;Royal Society of Chemistry (RSC)
摘要:	摘要： The biocompatibility of anodized titanium (TiO 2 ) was improved by electrophoretically deposited mineral (strontium (Sr), magnesium (Mg) and zinc (Zn)) substituted hydroxyapatite (M-HAP). The M-HAP layer was grown on the anodized Ti surface at different deposition temperatures (room temperature, 60 and 80 °C). The phases and morphologies of the M-HAP layers were influenced by the deposition temperature. The coatings were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Scanning electron microscopy equipped with energy dispersive X-ray analysis (SEM-EDX). Also, the effects of temperature and the mineral substitution of Sr, Mg and Zn for Ca on the physiochemical and biological properties of the M-HAP coatings were evaluated by the mechanical strength, ion dissolution and proliferation, alkaline phosphatase (ALP) activity and osteogenic expression of osteoblast like cells MG66 (HOS). Thus, the M-HAP deposition of TiO 2 will serve as a potential candidate for orthopedic applications. 出版者： Royal Society of Chemistry (RSC) 出版日期： 2015-01-01 出處： RSC Advances, 2015-01, Vol.5 (73), p.58980-58988 資源來源： Royal Society of Chemistry 識別號： ISSN: 2046-2069 識別號： EISSN: 2046-2069 識別號： DOI: 10.1039/c5ra11037h
显示于类别:	[化學工程與材料工程學系 ] 期刊論文

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