Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cells

NCUIR > Engineering College > Department of Chemical and Materials Engineering > journal & Dissertation > Item 987654321/101400

Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/101400

Title:	Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cells
Authors:	樋口亞紺;Higuchi, Akon;Ling, Qing-Dong;Kumar, S. Suresh;Chang, Yung;Alarfaj, Abdullah A;Munusamy, Murugan A;Murugan, Kadarkarai;Hsu, Shih-Tien;Umezawa, Akihiro
Contributors:	工學院化學工程與材料工程學系
Keywords:	biocompatible materials;Biomaterials;Biomedical materials;cell culture;chemistry;Cues;Culture;Differentiation;electrical treatment;embryonic germ layers;embryonic stem cells;forces;humans;induced pluripotent stem cells;Stem cells;Stimulation;Surgical implants;topography
Date:	2015-01-01
Issue Date:	2026-04-21 14:32:42 (UTC+8)
Publisher:	Royal Society of Chemistry;England: Royal Society of Chemistry (RSC)
Abstract:	摘要： Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different cell types originating from all three germ layers. This review discusses physical cues from natural and synthetic biomaterials that guide the differentiation of hESCs and hiPSCs into several different lineages. We place special focus on how the hPSC differentiation fate is affected by (a) the elasticity of biomaterials used for hPSC culture, (b) the topography of biomaterials used for hPSC culture, and (c) the mechanical forces associated with biomaterials (stretching and electrical stimulation via biomaterials) used for hPSC culture. Differentiation methods of hPSCs into specific cell lineages. Differentiation of hPSCs via EB formation (types AB, A-D) or without EB formation (types E-H). 其他題名： J Mater Chem B 出版者： England: Royal Society of Chemistry (RSC) 出版日期： 2015-01-01 出處： Journal of Materials Chemistry B, 2015-01, Vol.3 (41), p.8032-8058 資源來源： Royal Society of Chemistry 識別號： ISSN: 2050-750X 識別號： ISSN: 2050-7518 識別號： EISSN: 2050-7518 識別號： DOI: 10.1039/c5tb01276g 識別號： PMID: 32262861
Appears in Collections:	[Department of Chemical and Materials Engineering] journal & Dissertation

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