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    Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/101758


    Title: Odontogenic epithelial stem cells: Hidden sources
    Authors: 樋口亞紺;Padma Priya, Sivan;Higuchi, Akon;Abu Fanas, Salem;Pooi Ling, Mok;Kumari Neela, Vasantha;Sunil, P M;Saraswathi, T R;Murugan, Kadarkarai;Alarfaj, Abdullah A;Munusamy, Murugan A;Kumar, Suresh
    Contributors: 工學院化學工程與材料工程學系
    Keywords: 13/100;13/107;14/19;631/532/2118/2074;631/61/2320;Animals;Humans;Laboratory Medicine;Medicine;Medicine & Public Health;mini-review;Odontogenesis;Pathology;Stem Cells
    Date: 2015-12-01
    Issue Date: 2026-04-21 14:43:14 (UTC+8)
    Publisher: Nature Publishing Group;New York: Elsevier Inc
    Abstract: 摘要: The ultimate goal of dental stem cell research is to construct a bioengineered tooth. Tooth formation occurs based on the well-organized reciprocal interaction of epithelial and mesenchymal cells. The dental mesenchymal stem cells are the best explored, but because the human odontogenic epithelium is lost after the completion of enamel formation, studies on these cells are scarce. The successful creation of a bioengineered tooth is achievable only when the odontogenic epithelium is reconstructed to produce a replica of natural enamel. This article discusses the untapped sources of odontogenic epithelial stem cells in humans, such as those present in the active dental lamina in postnatal life, in remnants of dental lamina (the gubernaculum cord), in the epithelial cell rests of Malassez, and in reduced enamel epithelium. The possible uses of these stem cells in regenerative medicine, not just for enamel formation, are discussed.
    其他題名: Lab Invest
    出版者: New York: Elsevier Inc
    出版日期: 2015-12
    出處: Laboratory investigation, 2015-12, Vol.95 (12), p.1344-1352
    資源來源: Alma/SFX Local Collection
    版權: 2015 United States & Canadian Academy of Pathology
    版權: United States & Canadian Academy of Pathology 2015
    版權: Copyright Nature Publishing Group Dec 2015
    識別號: ISSN: 0023-6837
    識別號: ISSN: 1530-0307
    識別號: EISSN: 1530-0307
    識別號: DOI: 10.1038/labinvest.2015.108
    識別號: PMID: 26367485
    Appears in Collections:[Department of Chemical and Materials Engineering] journal & Dissertation

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